MRS 1845

MRS 1845 Structure
MRS 1845 structure
Common Name MRS 1845
CAS Number 544478-19-5 Molecular Weight 398.41
Density 1.318g/cm3 Boiling Point 530.8ºC at 760 mmHg
Molecular Formula C21H22N2O6 Melting Point N/A
MSDS Chinese USA Flash Point 274.8ºC

GPR35 activation reduces Ca2+ transients and contributes to the kynurenic acid-dependent reduction of synaptic activity at CA3-CA1 synapses.

PLoS ONE 8 , e82180, (2013)

Limited information is available on the brain expression and role of GPR35, a Gi/o coupled receptor activated by kynurenic acid (KYNA). In mouse cultured astrocytes, we detected GPR35 transcript using RT-PCR and we found that KYNA (0.1 to 100 µM) decreased fo...