544478-19-5

544478-19-5 structure

Name: MRS 1845
Chemical Name: 5-O-ethyl 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1-prop-2-ynyl-4H-pyridine-3,5-dicarboxylate
CAS Number: 544478-19-5
Molecular Formula: C₂₁H₂₂N₂O₆
Molecular Weight: 398.41
Catalog: Signaling Pathways Membrane Transporter/Ion Channel Calcium Channel
Create Date: 2017-08-22 12:25:21
Modify Date: 2025-08-25 11:41:11
MRS1845 is a Ca2+ channel blocker with relative specificity for store-operated calcium entry (SOCE) channels[1].

Name	5-O-ethyl 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1-prop-2-ynyl-4H-pyridine-3,5-dicarboxylate
Synonyms	MRS 1845 N-Propargylnitrendipene

Description	MRS1845 is a Ca2+ channel blocker with relative specificity for store-operated calcium entry (SOCE) channels[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel Research Areas >> Cardiovascular Disease
Target	Ca2+ channel[1]
References	[1]. Lee C, et al. Store-operated calcium channel inhibition attenuates neutrophil function and postshock acute lung injury. J Trauma. 2005 Jul;59(1):56-63.

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RIDADR	NONH for all modes of transport