N-ACETYLTHIOUREA

N-ACETYLTHIOUREA Structure
N-ACETYLTHIOUREA structure
Common Name N-ACETYLTHIOUREA
CAS Number 591-08-2 Molecular Weight 134.157
Density 1.4±0.1 g/cm3 Boiling Point 208.6ºC at 760 mmHg
Molecular Formula C3H6N2O2S Melting Point 165-169 °C(lit.)
MSDS Chinese USA Flash Point N/A
Symbol GHS06
GHS06
Signal Word Danger

[Modification of the thiobarbituric method for determining sialic acids in biological material].

Lab. Delo (9) , 15-8, (1989)

The authors have examined the possibility of replacing sodium arsenite with acetyl thiourea and of using butanol acidified with phosphoric acid in measuring sialic acids in biologic material. The results evidence a sufficient specificity, reproducibility, hig...

Oxyhalogen-sulfur chemistry: kinetics and mechanism of oxidation of N-acetylthiourea by chlorite and chlorine dioxide.

J. Phys. Chem. A 110(7) , 2396-410, (2006)

The oxidation reactions of N-acetylthiourea (ACTU) by chlorite and chlorine dioxide were studied in slightly acidic media. The ACTU-ClO(2)(-) reaction has a complex dependence on acid with acid catalysis in pH > 2 followed by acid retardation in higher acid c...

Formation and structure elucidation of N-(2,3,4-tri-O-acetyl-beta-D-glucopyranosyl)-N'-acetylthiourea.

Carbohydr. Res. 344(1) , 134-5, (2009)

Treatment with concd HCl/MeOH transformed N-(tetra-O-acetyl-beta-D-glucopyranosyl)-N'-acetylthiourea, via selective cleavage of the primary alcoholic ester group, into the title compound.

Histone deacetylase activators: N-acetylthioureas serve as highly potent and isozyme selective activators for human histone deacetylase-8 on a fluorescent substrate.

Bioorg. Med. Chem. Lett. 21(19) , 5920-3, (2011)

We report, for the first time, that certain N-acetylthiourea derivatives serve as highly potent and isozyme selective activators for the recombinant form of human histone deacetylase-8 in the assay system containing Fluor-de-Lys as a fluorescent substrate. Th...