3,4-Difluorobenzyl bromide

3,4-Difluorobenzyl bromide Structure
3,4-Difluorobenzyl bromide structure
Common Name 3,4-Difluorobenzyl bromide
CAS Number 85118-01-0 Molecular Weight 207.015
Density 1.6±0.1 g/cm3 Boiling Point 195.5±25.0 °C at 760 mmHg
Molecular Formula C7H5BrF2 Melting Point N/A
MSDS Chinese USA Flash Point 79.4±0.0 °C
Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger

The design and synthesis of novel, phosphonate-containing transient receptor potential melastatin 8 (TRPM8) antagonists.

Bioorg. Med. Chem. Lett. 22(8) , 2922-6, (2012)

A series of benzothiophene-based phosphonates was synthesized and many analogs within the series were shown to be potent antagonists of the TRPM8 channel. The compounds were obtained as a racemic mixture in 5 synthetic steps, and were tested for TRPM8 antagon...