Enalaprilat Dihydrate

Enalaprilat Dihydrate Structure
Enalaprilat Dihydrate structure
Common Name Enalaprilat Dihydrate
CAS Number 84680-54-6 Molecular Weight 384.424
Density N/A Boiling Point 563.5ºC at 760 mmHg
Molecular Formula C18H28N2O7 Melting Point 211-215°C
MSDS Chinese USA Flash Point 294.6ºC

Evaluation of a rapid method for the therapeutic drug monitoring of aliskiren, enalapril and its active metabolite in plasma and urine by UHPLC-MS/MS.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 980 , 79-87, (2015)

Given the increasing popularity of aliskiren, particularly in combination with angiotensin converting enzyme inhibitor (e.g. enalapril), it is important to determine whether its use in combination with these agents is associated with potentially life threaten...

Role of multidrug resistance-associated protein 4 in the basolateral efflux of hepatically derived enalaprilat.

Drug Metab. Dispos. 42(9) , 1567-74, (2014)

Hepatic uptake and efflux transporters govern the systemic and hepatic exposure of many drugs and metabolites. Enalapril is a pharmacologically inactive prodrug of enalaprilat. Following oral administration, enalapril is converted to enalaprilat in hepatocyte...

Enalaprilat.

Dimens. Crit. Care Nurs. 19(2) , 22, (2000)

Major contribution of the medial amygdala to hypertension in BPH/2J genetically hypertensive mice.

Hypertension 63(4) , 811-8, (2014)

BPH/2J mice are recognized as a neurogenic model of hypertension primarily based on overactivity of the sympathetic nervous system and greater neuronal activity in key autonomic cardiovascular regulatory brain regions. The medial amygdala (MeAm) is a forebrai...

Systemic and coronary haemodynamics and pharmacodynamics of enalapril and enalaprilat in congestive heart failure.

Drugs 39 Suppl 4 , 29-40; discussion 41-2, (1990)

Enalapril is an effective angiotensin-converting enzyme (ACE) inhibitor which produces salutary, beneficial haemodynamic effects in patients with congestive heart failure. Enalapril also produces beneficial neurohumoral changes, as well as improving abnormal ...