(2-Phenylethyl)boronic acid

(2-Phenylethyl)boronic acid Structure
(2-Phenylethyl)boronic acid structure
Common Name (2-Phenylethyl)boronic acid
CAS Number 34420-17-2 Molecular Weight 149.983
Density 1.1±0.1 g/cm3 Boiling Point 310.4±35.0 °C at 760 mmHg
Molecular Formula C8H11BO2 Melting Point 76-81 °C(lit.)
MSDS Chinese USA Flash Point 141.5±25.9 °C

Structure of a tetrahedral transition state complex of alpha-chymotrypsin dimer at 1.8-A resolution.

J. Biol. Chem. 262(16) , 7737-43, (1987)

A 1.8-A resolution x-ray crystallographic restrained least squares refinement has been carried out on the phenylethane boronic acid (PEBA) complex of alpha-chymotrypsin dimer (alpha-CHT), and it has been compared to the 1.67-A resolution structure of the nati...

Compounds that inhibit chymotrypsin and cell replication.

Biochem. Pharmacol. 35(20) , 3587-91, (1986)

Several compounds have been tested for their ability to inhibit bovine pancreatic alpha-chymotrypsin (Ki) and their ability to inhibit cell replication (IC50). There is good agreement over three orders of magnitude between the Ki and the IC50 values of these ...

A calorimetric investigation of the binding of indole and phenylethane boronic acid to chymotrypsin.

J. Biol. Chem. 258(4) , 2135-42, (1983)

The heat of formation of the chymotrypsin-phenylethane boronic acid complex has been observed calorimetrically from pH 4 to 8 at 25 degrees C and is found to be pH-dependent, changing from near -6 kcal/mol at pH 4 to -13 kcal/mol at pH 8. The heat of formatio...