Danofloxacine
Danofloxacine structure
|
Common Name | Danofloxacine | ||
|---|---|---|---|---|
| CAS Number | 112398-08-0 | Molecular Weight | 357.379 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 569.3±50.0 °C at 760 mmHg | |
| Molecular Formula | C19H20FN3O3 | Melting Point | 268-272ºC | |
| MSDS | Chinese USA | Flash Point | 298.1±30.1 °C | |
|
Multiresidue determination of fluoroquinolones in poultry muscle and kidney according to the regulation 2002/657/EC. A systematic comparison of two different approaches: Liquid chromatography coupled to high-resolution mass spectrometry or tandem mass spectrometry.
J. Chromatogr. A. 1379 , 83-91, (2015) This work involved the optimization and validation of two methods according to the Commission Decision 2002/657/EC directives for determining fluoroquinolones residues in samples of poultry muscle and kidney: ciprofloxacin, danofloxacin, difloxacin, enrofloxa... |
|
|
Simultaneous determination of 38 veterinary antibiotic residues in raw milk by UPLC-MS/MS.
Food Chem. 181 , 119-26, (2015) A selective and rapid method has been developed to determine, simultaneously, 38 veterinary antibiotic residues in raw milk by ultra-high-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). One milliliter of raw milk was diluted with 0.5 ... |
|
|
Decay mechanisms of protonated 4-quinolone antibiotics after electrospray ionization and ion activation.
J. Am. Soc. Mass Spectrom. 25(11) , 1974-86, (2014) This study presents a detailed experimental investigation of charge isomers of protonated 4-quinolone antibiotics molecules formed during electrospray ionization (ESI) with proposed dissociation mechanisms after collisional activation. Piperazinyl quinolones ... |
|
|
The development and validation of a rapid method for the determination of antimicrobial agent residues in milk and meat using ultra performance liquid chromatography coupled to quadrupole--Orbitrap mass spectrometry.
J. Pharm. Biomed. Anal. 102 , 184-92, (2014) A new multi-class method has been developed for the identification and quantification of the residues of 26 antibiotics from different classes (sulfonamides, macrolides, tetracyclines, penicillins, and quinolones) in milk and meat by ultra performance liquid ... |
|
|
Multi-residue Determination of Polar Veterinary Drugs in Livestock and Fishery Products by Liquid Chromatography/Tandem Mass Spectrometry.
J. AOAC Int. 98(1) , 230-47, (2015) Residues of 37 polar veterinary drugs belonging to six families (quinolones, tetracyclines, macrolides, lincosamides, sulfonamides, and others) in livestock and fishery products were determined using a validated LC-MS/MS method. There were two key points in s... |
|
|
Development of a novel genetically modified bioluminescent-bacteria-based assay for detection of fluoroquinolones in animal-derived foods.
Anal. Bioanal. Chem 406(30) , 7899-910, (2014) Fluoroquinolones (FQNs) are broad-spectrum antibacterial agents widely used in animal husbandry and aquaculture. The residues and antimicrobial resistance of such antibiotics are a major public health concern. To realize multianalyte detection of FQN residues... |
|
|
A simple, fast and cheap non-SPE screening method for antibacterial residue analysis in milk and liver using liquid chromatography-tandem mass spectrometry.
Talanta 129 , 374-83, (2014) In routine laboratory work, screening methods for multiclass analysis can process a large number of samples in a short time. The main challenge is to develop a methodology to detect as many different classes of residues as possible, combined with speed and lo... |
|
|
Pharmacokinetics of danofloxacin and N-desmethyldanofloxacin in adult horses and their concentration in synovial fluid.
J. Vet. Pharmacol. Ther. 38(2) , 123-9, (2015) The objectives of this study were to investigate the pharmacokinetics of danofloxacin and its metabolite N-desmethyldanofloxacin and to determine their concentrations in synovial fluid after administration by the intravenous, intramuscular or intragastric rou... |
|
|
In vitro selection of RNA aptamers that selectively bind danofloxacin.
Biochem. Biophys. Res. Commun. 448(4) , 397-402, (2014) Danofloxacin is a synthetic fluoroquinolone with broad spectrum antibacterial activity that is used for the treatment of respiratory diseases in animal husbandry. However, danofloxacin has many adverse reactions and is toxic to humans. Especially, it detrimen... |
|
|
Pharmacodynamics of antimicrobials against Mycoplasma mycoides mycoides small colony, the causative agent of contagious bovine pleuropneumonia.
PLoS ONE 7(8) , e44158, (2012) Mycoplasma mycoides subspecies mycoides Small Colony (MmmSC) is the causative agent of Contagious Bovine Pleuropneumonia (CBPP), a disease of substantial economic importance in sub-Saharan Africa. Failure of vaccination to curtail spread of this disease has l... |