Allyl isothiocyanate
Allyl isothiocyanate structure
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Common Name | Allyl isothiocyanate | ||
|---|---|---|---|---|
| CAS Number | 57-06-7 | Molecular Weight | 99.154 | |
| Density | 0.9±0.1 g/cm3 | Boiling Point | 151.9±9.0 °C at 760 mmHg | |
| Molecular Formula | C4H5NS | Melting Point | -80 °C | |
| MSDS | Chinese USA | Flash Point | 36.3±26.5 °C | |
| Symbol |
GHS02, GHS06, GHS08, GHS09 |
Signal Word | Danger | |
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Goshajinkigan, a traditional Japanese medicine, prevents oxaliplatin-induced acute peripheral neuropathy by suppressing functional alteration of TRP channels in rat.
J. Pharmacol. Sci. 125(1) , 91-8, (2014) The acute peripheral neuropathy induced by oxaliplatin treatment occurs very frequently and is aggravated by exposure to cold. Goshajinkigan (GJG), a traditional Japanese (kampo) medicine, was recently shown to be effective against oxaliplatin-induced acute n... |
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TRPV1 sensitization mediates postinflammatory visceral pain following acute colitis.
Am. J. Physiol. Gastrointest. Liver Physiol. 309 , G87-99, (2015) Quiescent phases of inflammatory bowel disease (IBD) are often accompanied by chronic abdominal pain. Although the transient receptor potential vanilloid 1 (TRPV1) ion channel has been postulated as an important mediator of visceral hypersensitivity, its func... |
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Only a minority of broad-range detoxification genes respond to a variety of phytotoxins in generalist Bemisia tabaci species.
Sci. Rep. 5 , 17975, (2015) Generalist insect can utilize two different modes for regulating their detoxification genes, the constitutive mode and the induced mode. Here, we used the Bemisia tabaci sibling species MEAM1 and MED, as a model system for studying constitutive and induced de... |
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Mechanisms Underlying the Scratching Behavior Induced by the Activation of Proteinase-Activated Receptor-4 in Mice.
J. Invest. Dermatol. 135 , 2484-91, (2015) A role for proteinase-activated receptor-4 (PAR-4) was recently suggested in itch sensation. Here, we investigated the mechanisms underlying the pruriceptive actions of the selective PAR-4 agonist AYPGKF-NH2 (AYP) in mice. Dorsal intradermal (i.d.) administra... |
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Influence of the antimicrobial compound allyl isothiocyanate against the Aspergillus parasiticus growth and its aflatoxins production in pizza crust.
Food Chem. Toxicol. 83 , 222-8, (2015) Aflatoxins (AFs) are secondary metabolites produced by different species of Aspergillus, such as Aspergillus flavus and Aspergillus parasiticus, which possess mutagenic, teratogenic and carcinogenic activities in humans. In this study, active packaging devices... |
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Long-lasting facilitation of respiratory rhythm by treatment with TRPA1 agonist, cinnamaldehyde.
J. Neurophysiol. 114 , 989-98, (2015) The transient receptor potential (TRP) channels are widely distributed in the central nervous system (CNS) and peripheral nervous system. We examined the effects of TRP ankyrin 1 (TRPA1) agonists (cinnamaldehyde and allyl isothiocyanate) on respiratory rhythm... |
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Direct evidence for functional TRPV1/TRPA1 heteromers.
Pflugers Arch. 466(12) , 2229-41, (2014) Transient receptor potential cation channel, subfamily V, member 1 (TRPV1) plays a key role in sensing environmental hazards and in enhanced pain sensation following inflammation. A considerable proportion of TRPV1-expressing cells also express transient rece... |
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Gallic acid functions as a TRPA1 antagonist with relevant antinociceptive and antiedematogenic effects in mice.
Naunyn Schmiedebergs Arch. Pharmacol. 387(7) , 679-89, (2014) The transient receptor potential ankyrin 1 (TRPA1) has been identified as a relevant target for the development of novel analgesics. Gallic acid (GA) is a polyphenolic compound commonly found in green tea and various berries and possesses a wide range of biol... |
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Mechanotransduction of trigeminal ganglion neurons innervating inner walls of rat anterior eye chambers.
Am. J. Physiol. Cell Physiol. 309 , C1-10, (2015) To address mechanoreceptive roles of trigeminal ganglion (TG) nerve endings in the inner walls of rat anterior eye chambers, we investigated the mechanotransduction process and mechanosensitive (MS) channel on somata of TG neurons innervating this area in vit... |
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Maresin 1 Inhibits TRPV1 in Temporomandibular Joint-Related Trigeminal Nociceptive Neurons and TMJ Inflammation-Induced Synaptic Plasticity in the Trigeminal Nucleus.
Mediators Inflamm. 2015 , 275126, (2015) In the trigeminal system, disruption of acute resolution processing may lead to uncontrolled inflammation and chronic pain associated with the temporomandibular joint (TMJ). Currently, there are no effective treatments for TMJ pain. Recently, it has been reco... |