3-(Trifluoromethyl)benzyl chloride

3-(Trifluoromethyl)benzyl chloride Structure
3-(Trifluoromethyl)benzyl chloride structure
Common Name 3-(Trifluoromethyl)benzyl chloride
CAS Number 705-29-3 Molecular Weight 194.581
Density 1.3±0.1 g/cm3 Boiling Point 179.1±35.0 °C at 760 mmHg
Molecular Formula C8H6ClF3 Melting Point N/A
MSDS Chinese USA Flash Point 48.9±0.0 °C
Symbol GHS02 GHS05
GHS02, GHS05
Signal Word Danger

Distributed Drug Discovery, Part 3: using D(3) methodology to synthesize analogs of an anti-melanoma compound.

J. Comb. Chem. 11(1) , 34-43, (2009)

For the successful implementation of Distributed Drug Discovery (D(3)) (outlined in the accompanying Perspective), students, in the course of their educational laboratories, must be able to reproducibly make new, high quality, molecules with potential for bio...

Distributed Drug Discovery, Part 2: global rehearsal of alkylating agents for the synthesis of resin-bound unnatural amino acids and virtual D(3) catalog construction.

J. Comb. Chem. 11 , 14-33, (2009)

Distributed Drug Discovery (D(3)) proposes solving large drug discovery problems by breaking them into smaller units for processing at multiple sites. A key component of the synthetic and computational stages of D(3) is the global rehearsal of prospective rea...

Synthesis and biological evaluation of a series of dithiocarbamates as new cholinesterase inhibitors.

Arch. Pharm. (Weinheim) 346(8) , 571-6, (2013)

In the present paper, a novel series of dithiocarbamates was synthesized via the treatment of 4-(trifluoromethyl)benzyl chloride with appropriate sodium salts of N,N-disubstituted dithiocarbamic acids. The chemical structures of the compounds were elucidated ...

Synthesis of poly (arylene ether amide) s containing CF 3 groups by nitro displacement reaction of AB-type monomers. Lee HS and Kim SY.

Macromol. Rapid Commun. 23(12) , 665-71, (2002)