N-Octylpyrrolidone

N-Octylpyrrolidone Structure
N-Octylpyrrolidone structure
Common Name N-Octylpyrrolidone
CAS Number 2687-94-7 Molecular Weight 197.317
Density 0.9±0.1 g/cm3 Boiling Point 303.1±0.0 °C at 760 mmHg
Molecular Formula C12H23NO Melting Point −25 °C(lit.)
MSDS Chinese USA Flash Point 129.0±9.9 °C
Symbol GHS05 GHS09
GHS05, GHS09
Signal Word Danger

Influence of the permeation enhancers 1-alkyl-2-pyrrolidones on permeant partitioning into the stratum corneum.

J. Pharm. Sci. 87(2) , 209-14, (1998)

In a previous study, the enhancing effects of a series of 1-alkyl-2-pyrrolidones (APs; 1-ethyl, 1-butyl, 1-hexyl, and 1-octyl-2-pyrrolidone) on the transport of steroidal permeants across hairless mouse skin were investigated via a parallel pathway skin model...