HSDB 3314
HSDB 3314 structure
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Common Name | HSDB 3314 | ||
|---|---|---|---|---|
| CAS Number | 67-96-9 | Molecular Weight | 398.66400 | |
| Density | 1.003 g/cm3 | Boiling Point | 499.5ºC at 760 mmHg | |
| Molecular Formula | C28H46O | Melting Point | 131ºC | |
| MSDS | Chinese USA | Flash Point | 217.6ºC | |
| Symbol |
GHS06 |
Signal Word | Danger | |
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Prevalence and correction of 25(OH) vitamin D deficiency in peritoneal dialysis patients.
Perit. Dial. Int. 25(4) , 362-6, (2005) Peritoneal dialysis (PD) patients are at risk for 25(OH) vitamin D deficiency due to effluent loss in addition to traditional risk factors.To measure 25(OH) vitamin D deficiency in prevalent PD patients, to evaluate a replacement dose, and to determine the ef... |
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3-nitropropionic acid-induced hydrogen peroxide, mitochondrial DNA damage, and cell death are attenuated by Bcl-2 overexpression in PC12 cells.
Brain Res. Mol. Brain Res. 133(2) , 215-23, (2005) 3-nitropropionic acid (3-NPA), a complex II inhibitor of the electron transport chain, causes Huntington disease-like symptoms after administration into animals. However, primary mechanisms of cell death are not clearly understood. This study tested the hypot... |
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Calpain-mediated AQP2 proteolysis in inner medullary collecting duct.
Biochem. Biophys. Res. Commun. 303(1) , 52-8, (2003) Vitamin D-elicited hypercalcemia/hypercalciuria is associated with polyuria in humans and in animal models. In rats, dihydrotachysterol (DHT) induces AQP2 water channel downregulation despite unaltered AQP2 mRNA expression and thus we investigated the mechani... |
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Functional modulation of the ATP-sensitive potassium channel by extracellular signal-regulated kinase-mediated phosphorylation.
Neuroscience 152(2) , 371-80, (2008) ATP-sensitive potassium (K(ATP)) channels play an important role in controlling insulin secretion and vascular tone as well as protecting neurons under metabolic stress. We have previously demonstrated that stimulation of the K(ATP) channel by nitric oxide (N... |
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Early apoptotic and late necrotic components associated with altered Ca2+ homeostasis in a peptide-delivery model of polyglutamine-induced neuronal death.
J. Neurosci. Res. 80(4) , 549-61, (2005) The mechanisms by which polyglutamine expansion causes common features of neuronal death remain unclear. Here we describe an approach for delivering polyglutamine expansions directly into cultured sympathetic neurons. Glutamine (Q) residues (n = 10, 22, 30) w... |
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Neurotensin-induced Cl(-) current in guinea-pig dorsal root ganglion cells.
Eur. J. Pharmacol. 404(1-2) , 69-78, (2000) In guinea-pig dorsal root ganglion cells held under voltage-clamp at -80 mV, neurotensin elicited an inward current (I(NT)) whose amplitude increased with increasing neurotensin concentration (40-4000 nM). The effect was blocked by a nonpeptide neurotensin an... |
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Tumor necrosis factor-alpha induces renal cyclooxygenase-2 expression in response to hypercalcemia.
Prostaglandins Other Lipid Mediat. 99(1-2) , 45-50, (2012) The effect of tumor necrosis factor-alpha (TNF) on cyclooxygenase-2 (COX-2) expression in the renal outer medulla (OM) was determined in a model of dihydrotachysterol (DHT)-induced hypercalcemia. Increases in serum calcium and water intake were observed durin... |
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Impact of parathyroid status and Ca and vitamin-D supplementation on bone mass and muscle-bone relationships in 208 Belarussian children after thyroidectomy because of thyroid carcinoma.
Exp. Clin. Endocrinol. Diabetes 112(8) , 444-50, (2004) This observational study analyzes Ca-P metabolism and its impact on bone mass accrual and density and the muscle-bone mass/mass relationships in male and female children and adolescents who were parathyroidectomized because of thyroid carcinoma. Two hundred a... |
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Dihydrotachysterol therapy for hypoparathyroidism: consequences of inadequate monitoring. Five cases and a review.
Exp. Clin. Endocrinol. Diabetes 113(7) , 376-80, (2005) The half synthetic Vitamin D analogue dihydrotachysterol (DHT) is widely used for hypocalcaemic hypoparathyroidism following surgical removal of parathyroids. Such treatment generally initiated by surgeons right after surgery has to be continued in clinical p... |
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Current therapy of hypoparathyroidism--a survey of German endocrinology centers.
Exp. Clin. Endocrinol. Diabetes 105(4) , 237-41, (1997) Hypoparathyroidism is a rare disease with hypocalcemia as the leading symptom. In adults, hypocalcemia is mainly due to postoperative hypoparathyroidism. Hypoparathyroidism requires lifelong therapy with vitamin D or metabolites. Genuine vitamin D3 (Vigantol)... |