UCL-1848 trifluoroacetate salt

UCL-1848 trifluoroacetate salt Structure
UCL-1848 trifluoroacetate salt structure
Common Name UCL-1848 trifluoroacetate salt
CAS Number 201147-53-7 Molecular Weight 766.65100
Density N/A Boiling Point N/A
Molecular Formula C34H35F9N4O6 Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

bis-Quinolinium cyclophanes: 8,14-diaza-1,7(1, 4)-diquinolinacyclotetradecaphane (UCL 1848), a highly potent and selective, nonpeptidic blocker of the apamin-sensitive Ca(2+)-activated K(+) channel.

J. Med. Chem. 43 , 3478-3481, (2000)

Therapeutic scope of modulation of non-voltage-gated cation channels.

Drug Discov. Today 10 , 129-137, (2005)

Although widely regarded as attractive drug targets, less than a tenth of known ion channels are currently commercially exploited as therapeutic targets. Historically, drug discovery efforts on ion channel targets have been encumbered by a lack of molecular a...