Fluorescein di(β-D-galactopyranoside)

Fluorescein di(β-D-galactopyranoside) Structure
Fluorescein di(β-D-galactopyranoside) structure
Common Name Fluorescein di(β-D-galactopyranoside)
CAS Number 17817-20-8 Molecular Weight 656.58700
Density 1.74 g/cm3 Boiling Point 974.8ºC at 760 mmHg
Molecular Formula C32H32O15 Melting Point 200-203ºC (dec.)
MSDS Chinese USA Flash Point 316.5ºC

High-throughput screening with nanoimprinting 3D culture for efficient drug development by mimicking the tumor environment.

Biomaterials 51 , 278-89, (2015)

Anti-cancer drug development typically utilizes high-throughput screening with two-dimensional (2D) cell culture. However, 2D culture induces cellular characteristics different from tumors in vivo, resulting in inefficient drug development. Here, we report an...

Quantitative evaluation of DNA damage and mutation rate by atmospheric and room-temperature plasma (ARTP) and conventional mutagenesis.

Appl. Microbiol. Biotechnol. 99 , 5639-46, (2015)

DNA damage is the dominant source of mutation, which is the driving force of evolution. Therefore, it is important to quantitatively analyze the DNA damage caused by different mutagenesis methods, the subsequent mutation rates, and their relationship. Atmosph...

A programmable microfluidic static droplet array for droplet generation, transportation, fusion, storage, and retrieval.

Lab Chip 15 , 3677-86, (2015)

We present a programmable microfluidic static droplet array (SDA) device that can perform user-defined multistep combinatorial protocols. It combines the passive storage of aqueous droplets without any external control with integrated microvalves for discrete...

Coronavirus cell entry occurs through the endo-/lysosomal pathway in a proteolysis-dependent manner.

PLoS Pathog. 10(11) , e1004502, (2014)

Enveloped viruses need to fuse with a host cell membrane in order to deliver their genome into the host cell. While some viruses fuse with the plasma membrane, many viruses are endocytosed prior to fusion. Specific cues in the endosomal microenvironment induc...

Identification of a β-galactosidase transgene that provides a live-cell marker of transcriptional activity in growing oocytes and embryos.

Mol. Hum. Reprod. 21 , 583-93, (2015)

Identifying the events and molecular mechanisms that regulate oocyte growth has emerged as a key objective of research in human fertility, fuelled by evidence from human and animal studies indicating that disease and environmental factors can act on oocytes t...

Quantifying the Area at Risk in Reperfused ST-Segment-Elevation Myocardial Infarction Patients Using Hybrid Cardiac Positron Emission Tomography-Magnetic Resonance Imaging.

Circ. Cardiovasc. Imaging 9 , e003900, (2016)

Hybrid positron emission tomography and magnetic resonance allows the advantages of magnetic resonance in tissue characterizing the myocardium to be combined with the unique metabolic insights of positron emission tomography. We hypothesized that the area of ...

Hierarchical multivariate covariance analysis of metabolic connectivity.

J. Cereb. Blood Flow Metab. 34(12) , 1936-43, (2014)

Conventional brain connectivity analysis is typically based on the assessment of interregional correlations. Given that correlation coefficients are derived from both covariance and variance, group differences in covariance may be obscured by differences in t...

The role of tomatine adjuvant in antigen delivery for cross- presentation.

Curr. Drug Deliv. 12 , 342-50, (2015)

The aim of this study was to investigate the use of tomatine adjuvant to deliver soluble antigen for crosspresentation by bone marrow-derived dendritic cells (BMDCs). BMDCs were incubated with tomatine adjuvantovalbumin (OVA) complex and analyzed for antigen ...

18-Fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography scan for monitoring the therapeutic response in experimental Staphylococcus aureus foreign-body osteomyelitis.

J. Orthop. Surg. Res. 10 , 132, (2015)

18-Fluoro-2-deoxy-D-glucose positron emission tomography combined with computed tomography ((18)F-FDG PET/CT) scan is useful for diagnosis of osteoarticular infections. Whether (18)F-FDG PET/CT scanning may be used for therapeutic monitoring is not clear. The...

The Role of Nitric Oxide Synthase Uncoupling in Tumor Progression.

Mol. Cancer Res. 13 , 1034-43, (2015)

Here, evidence suggests that nitric oxide synthases (NOS) of tumor cells, in contrast with normal tissues, synthesize predominantly superoxide and peroxynitrite. Based on high-performance liquid chromatography analysis, the underlying mechanism for this uncou...