(1s,2s)-(+)-n-methylpseudoephedrine
(1s,2s)-(+)-n-methylpseudoephedrine structure
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Common Name | (1s,2s)-(+)-n-methylpseudoephedrine | ||
|---|---|---|---|---|
| CAS Number | 51018-28-1 | Molecular Weight | 179.25900 | |
| Density | 1.009g/cm3 | Boiling Point | 145ºC24 mm Hg(lit.) | |
| Molecular Formula | C11H17NO | Melting Point | 29-31ºC(lit.) | |
| MSDS | Chinese USA | Flash Point | >230 °F | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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The relevance of the urinary concentration of ephedrines in anti-doping analysis: determination of pseudoephedrine, cathine, and ephedrine after administration of over-the-counter medicaments.
Ther. Drug Monit. 31(4) , 520-6, (2009) This article describes a method for the detection and quantitation of cathine, pseudoephedrine, ephedrine, and methylephedrine in urine, using their deuterated analogues as internal standards and derivatization to form the corresponding trimethylsilyl derivat... |
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Comparison of contents of five ephedrine alkaloids in three official origins of Ephedra Herb in China by high-performance liquid chromatography.
J. Nat. Med. 65(3-4) , 623-8, (2011) In the present paper, a fast and economical HPLC method [on a Phenomenex Polar-RP column with a solution of (phosphoric acid:triethylamine:dibutylamine:water = 0.40:0.1:0.2:499.3) and methanol] is developed, and applied for the determination of norephedrine, ... |
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Simultaneous quantification of six ephedrines in a Mahwang preparation and in urine by high-performance liquid chromatography.
Biomed. Chromatogr. 19(5) , 337-42, (2005) A rapid and reliable high-performance liquid chromatographic method was developed and validated for the simultaneous determination of norephedrine (NE), norpseudoephedrine (NPE), ephedrine (E), pseudoephedrine (PE), methylephedrine (ME) and methylpseudoephedr... |
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Results of stability studies with doping agents in urine.
J. Anal. Toxicol. 31(9) , 543-8, (2007) For a correct interpretation of analytical results in doping control, knowledge on the stability of prohibited substances in the urinary matrix is a prerequisite. So far, limited data is available on the stability of prohibited substances in unaltered urine b... |
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Fast stereoselective reactions in electrosprayed Co(II)/neurotransmitter nanodroplets.
Chem. Commun. (Camb.) (22) , 2544-6, (2008) Collision induced dissociation (CID) of the m/z 479 ion, formed by ESI of Co(NO3)2-CH3OH solutions with either pure (1S,2S)-(+)-N-methylpseudoephedrine or its mixtures with (1S,2R)-(+)- or (1R,2S)-(-)-ephedrine, provides compelling evidence for fast, stereose... |
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Simultaneous determination of methylephedrine and noscapine in human plasma by liquid chromatography-tandem mass spectrometry.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 820(2) , 175-82, (2005) A selective and sensitive method has been developed and validated for simultaneous quantification of methylephedrine and noscapine in human plasma. Analytes were extracted from human plasma samples by liquid-liquid extraction, separated on a Diamonsil C18 col... |
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A prospective cohort study of pregnancy outcomes of women inadvertently exposed to methylephedrine in the 1st trimester of pregnancy.
J. Obstet. Gynaecol. 30(6) , 563-6, (2010) No information is currently available on the safety of methylephedrine, a component of various cold medications available in South Korea. With previous approval by an Institutional Review Board, 349 women inadvertently exposed to methylephedrine during the 1s... |
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Simultaneous determination of methylephedrine and pseudoephedrine in human urine by CE with electrochemiluminescence detection and its application to pharmacokeinetics.
Biomed. Chromatogr. 23(11) , 1138-44, (2009) A novel method for the determination of ephedra alkaloids (methylephedrine and pseudoephedrine) was developed by electrophoresis capillary (CE) separation and electrochemiluminesence detection (ECL). The use of ionic liquid (1-butyl-3-methylimidazolium tetraf... |
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Intoxication with over-the-counter antitussive medication containing dihydrocodeine and chlorpheniramine causes generalized convulsion and mixed acidosis.
Intern. Med. 47(11) , 1013-5, (2008) We report a 35-year-old man who was referred to our hospital with generalized convulsion and mixed acidosis presumably caused by abuse of SS-BRON tablets, an over-the-counter (OTC) antitussive medication sold in Japan. These tablets contain dihydrocodeine pho... |
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Application of dimethyl-beta-cyclodextrin as a chiral selector in capillary electrophoresis for enantiomer separation of ephedrine and related compounds in some drugs.
Biomed. Chromatogr. 19(6) , 447-53, (2005) Dimethyl-beta-cyclodextrin (DM-beta-CD) modified capillary electrophoresis has been developed for chiral separation of ephedrine and related compounds, such as (+/-)-norephedrine, (+/-)-N-methylephedrine, (+/-)-ephedrine and (+)-pseudoephedrine. The influence... |