DL-Histidine

DL-Histidine Structure
DL-Histidine structure
Common Name DL-Histidine
CAS Number 4998-57-6 Molecular Weight 191.615
Density 1.4±0.1 g/cm3 Boiling Point 458.9±35.0 °C at 760 mmHg
Molecular Formula C6H10ClN3O2 Melting Point 280-290ºC (dec.)
MSDS Chinese USA Flash Point 231.3±25.9 °C

Salicylic acid signaling controls the maturation and localization of the arabidopsis defense protein ACCELERATED CELL DEATH6.

Mol. Plant 7(8) , 1365-83, (2014)

ACCELERATED CELL DEATH6 (ACD6) is a multipass membrane protein with an ankyrin domain that acts in a positive feedback loop with the defense signal salicylic acid (SA). This study implemented biochemical approaches to infer changes in ACD6 complexes and local...

G-quadruplex conformation and dynamics are determined by loop length and sequence.

Nucleic Acids Res. 42(12) , 8106-14, (2014)

The quadruplex forming G-rich sequences are unevenly distributed throughout the human genome. Their enrichment in oncogenic promoters and telomeres has generated interest in targeting G-quadruplex (GQ) for an anticancer therapy. Here, we present a quantitativ...

Der p 11 is a major allergen for house dust mite-allergic patients suffering from atopic dermatitis.

J. Invest. Dermatol. 135(1) , 102-9, (2014)

House dust mites (HDMs) belong to the most potent indoor allergen sources worldwide and are associated with allergic manifestations in the respiratory tract and the skin. Here we studied the importance of the high-molecular-weight group 11 allergen from Derma...

Autoantibodies specific to D4GDI modulate Rho GTPase mediated cytoskeleton remodeling and induce autophagy in T lymphocytes.

J. Autoimmun. 58 , 78-89, (2015)

T lymphocytes from patients with Systemic Lupus Erythematosus (SLE) display multiple abnormalities, including increased cell activation, abnormal cell death by apoptosis and impairment of autophagy pathway. In the present study we report the presence of speci...

The CRE1 cytokinin pathway is differentially recruited depending on Medicago truncatula root environments and negatively regulates resistance to a pathogen.

PLoS ONE 10(1) , e0116819, (2015)

Cytokinins are phytohormones that regulate many developmental and environmental responses. The Medicago truncatula cytokinin receptor MtCRE1 (Cytokinin Response 1) is required for the nitrogen-fixing symbiosis with rhizobia. As several cytokinin signaling gen...

Investigation of a Degradant in a Biologics Formulation Buffer Containing L-Histidine.

Pharm. Res. 32 , 2625-35, (2015)

An unknown UV 280 nm absorbing peak was observed by SEC for protein stability samples formulated in L-histidine during a stress stability study. Understanding the source would enhance the confidence in the SEC results. We identified the unknown peak, studied ...

Structural insights into methanol-stable variants of lipase T6 from Geobacillus stearothermophilus.

Appl. Microbiol. Biotechnol. 99 , 9449-61, (2015)

Enzymatic production of biodiesel by transesterification of triglycerides and alcohol, catalyzed by lipases, offers an environmentally friendly and efficient alternative to the chemically catalyzed process while using low-grade feedstocks. Methanol is utilize...

Dissection of key determinants of cleavage activity in signal peptidase III (SPaseIII) PibD.

Extremophiles 18(5) , 905-13, (2014)

In Archaea, type IV prepilins and prearchaellins are processed by designated signal peptidase III (SPaseIII) prior to their incorporation into pili and the archaellum, respectively. These peptidases belong to the family of integral membrane aspartic acid prot...

Tyrosine phosphorylation of HSC70 and its interaction with RFC mediates methotrexate resistance in murine L1210 leukemia cells.

Cancer Lett. 357(1) , 231-41, (2014)

We previously identified and characterized a 66-68 kDa membrane-associated, tyrosine phosphorylated protein in murine leukemia L1210 cells as HSC70 which is a methotrexate (MTX)-binding protein. In order to further characterize the functional role of HSC70 in...

Highly efficient strategy for the heterologous expression and purification of soluble Cowpea chlorotic mottle virus capsid protein and in vitro pH-dependent assembly of virus-like particles.

J. Virol. Methods 225 , 23-9, (2015)

Obtaining pure and soluble viral capsid proteins (CPs) has been a major challenge in the fields of science and technology in recent decades. In many cases, the CPs can self-assemble in the absence of a viral genome, resulting in non-infectious, empty virus-li...