3'-sialyllactose
3'-sialyllactose structure
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Common Name | 3'-sialyllactose | ||
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| CAS Number | 35890-38-1 | Molecular Weight | 633.55100 | |
| Density | 1.72 g/cm3 | Boiling Point | 1132.8ºC at 760 mmHg | |
| Molecular Formula | C23H39NO19 | Melting Point | N/A | |
| MSDS | USA | Flash Point | 638.9ºC | |
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Molecular Characterisation of the Haemagglutinin Glycan-Binding Specificity of Egg-Adapted Vaccine Strains of the Pandemic 2009 H1N1 Swine Influenza A Virus.
Molecules 20 , 10415-34, (2015) The haemagglutinin (HA) glycan binding selectivity of H1N1 influenza viruses is an important determinant for the host range of the virus and egg-adaption during vaccine production. This study integrates glycan binding data with structure-recognition models to... |
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Rapid screening and identification of active ingredients in licorice extract interacting with V3 loop region of HIV-1 gp120 using ACE and CE-MS.
J. Pharm. Biomed. Anal. 111 , 28-35, (2015) The binding of envelope protein gp120 to glycosphingolipids is very important during the human immunodeficiency virus entering into the host cell. This step occurs in the V3 loop region in particularly. The conserved core sequence of V3 loop in gp120 was name... |
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Increased sialylation as a phenomenon in accommodation of the parasitic nematode Trichinella spiralis (Owen, 1835) in skeletal muscle fibres.
Folia Parasitol (Praha) 62 , (2015) The biology of sialic acids has been an object of interest in many models of acquired and inherited skeletal muscle pathology. The present study focuses on the sialylation changes in mouse skeletal muscle after invasion by the parasitic nematode Trichinella s... |
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Genetic engineering of Escherichia coli for the economical production of sialylated oligosaccharides.
J. Biotechnol. 134(3-4) , 261-5, (2008) We have previously described a microbiological process for the conversion of lactose into 3'sialyllactose and other ganglioside sugars by living Escherichia coli cells expressing the appropriate recombinant glycosyltransferase genes. In this system the activa... |
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Enzymatic Decoration of Prebiotic Galacto-oligosaccharides (Vivinal GOS) with Sialic Acid Using Trypanosoma cruzi trans-Sialidase and Two Bovine Sialoglycoconjugates as Donor Substrates.
J. Agric. Food Chem. 63 , 5976-84, (2015) Decoration of prebiotic galacto-oligosaccharides (GOS) with sialic acid yields mixtures of GOS and sialylated GOS (Sia-GOS), novel products that are expected to have both prebiotic and antiadhesive functionalities. The recombinantly produced trans-sialidase e... |
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Automated N-glycan profiling of a mutant Trypanosoma rangeli sialidase expressed in Pichia pastoris, using tandem mass spectrometry and bioinformatics.
Glycobiology 25 , 1350-61, (2015) A mutant Trypanosoma rangeli sialidase, Tr7, expressed in Pichia pastoris, exhibits significant trans-sialidase activity, and has been used for analytical-scale production of sialylated human milk oligosaccharides. Mass spectrometry-based site-specific N-glyc... |
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Sialyllactose in viral membrane gangliosides is a novel molecular recognition pattern for mature dendritic cell capture of HIV-1.
PLoS Biol. 10(4) , e1001315, (2012) HIV-1 is internalized into mature dendritic cells (mDCs) via an as yet undefined mechanism with subsequent transfer of stored, infectious virus to CD4+ T lymphocytes. Thus, HIV-1 subverts a DC antigen capture mechanism to promote viral spread. Here, we show t... |
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Sialic acid and crystal binding.
Kidney Int. 57(3) , 1072-82, (2000) We studied the role of cell surface sialic acid in the adherence of calcium oxalate monohydrate (COM) crystals to Madin-Darby canine kidney (MDCK) cells.Studies were performed with undifferentiated (crystal-binding) cells in subconfluent cultures and maturate... |
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[Animal model of distal myopathy with rimmed vacuoles/hereditary inclusion body myopathy and preclinical trial with sugar compounds].
Brain Nerve 62(6) , 601-7, (2010) Sialic acids are terminal sugars of glycolipids and glycoproteins and are involved in several cellular processes. Sialic acid biosynthesis occurs in the cytosol, where UDP-N-acetylglucosamine (GlcNAc) is sequentially converted to N-acetylmannosamine (ManNAc) ... |
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Structural analysis of the catalytic and binding sites of Clostridium botulinum neurotoxin B.
Nat. Struct. Biol. 7(8) , 693-9, (2000) Clostridium botulinum neurotoxins are among the most potent toxins to humans. The crystal structures of intact C. botulinum neurotoxin type B (BoNT/B) and its complex with sialyllactose, determined at 1. 8 and 2.6 A resolution, respectively, provide insight i... |