Nebivolol hydrochloride

Nebivolol hydrochloride Structure
Nebivolol hydrochloride structure
Common Name Nebivolol hydrochloride
CAS Number 152520-56-4 Molecular Weight 441.896
Density N/A Boiling Point 600.5ºC at 760 mmHg
Molecular Formula C22H26ClF2NO4 Melting Point 220-222ºC
MSDS Chinese USA Flash Point 316.9ºC
Symbol GHS07 GHS09
GHS07, GHS09
Signal Word Warning

Design, development and permeation studies of nebivolol hydrochloride from novel matrix type transdermal patches.

Adv. Biomed. Res. 2 , 62, (2013)

Nebivolol hydrochloride is a third generation β-blocker with highly selective β1-receptor antagonist with antihypertensive properties having plasma half life of 10 h and 12% oral bioavailability. The aim of the present investigation was to form matrix type tr...

Simultaneous estimation of amlodipine besylate and nebivolol hydrochloride in tablet dosage forms by reverse phase-high-performance liquid chromatographic using ultraviolet detection.

Pharm. Methods 2 , 9-14, (2013)

The present study aimed to develop and validate the simultaneous estimation of amlodipine and nebivolol in tablet dosage forms.An isocratic reversed phase high-performance liquid chromatographic (HPLC) method with ultraviolet detection at 268 nm has been deve...

Predicting in vivo cardiovascular properties of β-blockers from cellular assays: a quantitative comparison of cellular and cardiovascular pharmacological responses.

FASEB J. 25 , 4486-97, (2011)

β-Adrenoceptor antagonists differ in their degree of partial agonism. In vitro assays have provided information on ligand affinity, selectivity, and intrinsic efficacy. However, the extent to which these properties are manifest in vivo is less clear. Consciou...