N-acetyl-α-D-glucosamine

N-acetyl-α-D-glucosamine Structure
N-acetyl-α-D-glucosamine structure
Common Name N-acetyl-α-D-glucosamine
CAS Number 7512-17-6 Molecular Weight 221.208
Density 1.5±0.1 g/cm3 Boiling Point 595.4±50.0 °C at 760 mmHg
Molecular Formula C8H15NO6 Melting Point 201-204ºC
MSDS Chinese USA Flash Point 313.9±30.1 °C

Structural studies and biosynthetic aspects of the O-antigen polysaccharide from Escherichia coli O42.

Carbohydr. Res. 403 , 174-81, (2015)

The structure of the O-antigen polysaccharide (PS) from Escherichia coli O42 has been investigated by NMR spectroscopy as the main method, which was complemented with sugar analysis, mass spectrometry, and analysis of biosynthetic information. The O-specific ...

Melanoma cells homing to the brain: an in vitro model.

Biomed Res. Int. 2015 , 476069, (2015)

We developed an in vitro contact through-feet blood brain barrier (BBB) model built using type IV collagen, rat astrocytes, and human umbilical vein endothelial cells (HUVECs) cocultured through Transwell porous polycarbonate membrane. The contact between ast...

Substrates specialization in lipid compounds and hydrocarbons of Marinobacter genus.

Environ. Sci. Pollut. Res. Int. 22 , 15347-59, (2015)

The impact of petroleum contamination and of burrowing macrofauna on abundances of Marinobacter and denitrifiers was tested in marine sediment mesocoms after 3 months incubation. Quantification of this genus by qPCR with a new primer set showed that the main ...

Triterpene saponins with anti-inflammatory activity from the stems of Entada phaseoloides.

Fitoterapia 103 , 33-45, (2015)

The phytochemical investigation of the ethanol extract from the stems of Entada phaseoloides (L.) Merr (also called "Guo Gang Long") led to the isolation of eleven triterpene saponins (1-11). Their structures were elucidated by extensive spectroscopic methods...

A novel ion-exclusion chromatography–mass spectrometry method to measure concentrations and cycling rates of carbohydrates and amino sugars in freshwaters

J. Chromatogr. A. 1365 , 115-23, (2014)

• Novel HPLC–MS method for carbohydrate and amino sugar analysis in freshwaters. • Rapid and efficient determination without derivatization or sample pre-concentration. • Implementation of stable isotope tracers to study compound biogeochemical cycling. • Glu...

Exploring NAG-thiazoline and its derivatives as inhibitors of chitinolytic β-acetylglucosaminidases.

FEBS Lett. 589(1) , 110-6, (2015)

NAG-thiazoline (NGT) and its derivatives are well-known inhibitors against most β-acetylglucosaminidases (β-GlcNAcases) except for insect and bacterial chitinolytic β-GlcNAcases, including the molting-indispensable OfHex1 from the insect Ostrinia furnacalis. ...

Artemisia herba-alba essential oil from Buseirah (South Jordan): Chemical characterization and assessment of safe antifungal and anti-inflammatory doses.

J. Ethnopharmacol. 174 , 153-60, (2015)

Artemisia herba-alba Asso ("desert wormwood" in English; "armoise blanche" in French; "shaih" in Arabic), is a medicinal and strongly aromatic plant widely used in traditional medicine by many cultures since ancient times. It is used to treat inflammatory dis...

Plumbagin elicits differential proteomic responses mainly involving cell cycle, apoptosis, autophagy, and epithelial-to-mesenchymal transition pathways in human prostate cancer PC-3 and DU145 cells.

Drug Des. Devel. Ther. 9 , 349-417, (2015)

Plumbagin (PLB) has exhibited a potent anticancer effect in preclinical studies, but the molecular interactome remains elusive. This study aimed to compare the quantitative proteomic responses to PLB treatment in human prostate cancer PC-3 and DU145 cells usi...

Collagen-induced arthritis: severity and immune response attenuation using multivalent N-acetyl glucosamine.

Clin. Exp. Immunol. 177(1) , 121-33, (2014)

Rheumatoid arthritis is an autoimmunity leading to considerable impairment of quality of life. N-acetyl glucosamine (GlcNAc) has been described previously as a potent modulator of experimental arthritis in animal models and is used for osteoarthritis treatmen...

Studies on the Formation of Maillard and Caramelization Products from Glucosamine Incubated at 37 °C.

J. Agric. Food Chem. 63 , 6249-61, (2015)

This experiment compared the in vitro degradation of glucosamine (GlcN), N-acetylglucosamine, and glucose in the presence of NH3 incubated at 37 °C in phosphate buffer from 0.5 to 12 days. The reactions were monitored with UV-vis absorption and fluorescence e...