Sulfobromophthalein sodium
Sulfobromophthalein sodium structure
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Common Name | Sulfobromophthalein sodium | ||
|---|---|---|---|---|
| CAS Number | 123359-42-2 | Molecular Weight | 837.99700 | |
| Density | 0.866 g/mL at 25 °C(lit.) | Boiling Point | 227 °C | |
| Molecular Formula | C20H8Br4Na2O10S2 | Melting Point | -44°C | |
| MSDS | Chinese USA | Flash Point | 202 °F | |
| Symbol |
GHS08 |
Signal Word | Danger | |
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Expression of drug transporters and drug metabolizing enzymes in the bladder urothelium in man and affinity of the bladder spasmolytic trospium chloride to transporters likely involved in its pharmacokinetics.
Mol. Pharm. 12(1) , 171-8, (2015) The cationic, water-soluble quaternary trospium chloride (TC) is incompletely absorbed from the gut and undergoes wide distribution but does not pass the blood-brain barrier. It is secreted by the kidneys, liver, and intestine. To evaluate potential transport... |
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In vivo selective imaging and inhibition of leukemia stem-like cells using the fluorescent carbocyanine derivative, DiOC5(3).
Biomaterials 52 , 14-25, (2015) Elimination of leukemia stem cells (LSCs) is necessary for the destruction of malignant cell populations. Owing to the very small number of LSCs in leukemia cells, xenotransplantation studies are difficult in terms of functionally and pathophysiologically rep... |
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Evaluation of bone repair of critical size defects treated with simvastatin-loaded poly(lactic-co-glycolic acid) microspheres in rat calvaria.
J. Biomater. Appl. 29(7) , 965-76, (2015) Statins are hypolipemiant drugs with osteoinductive effect. We evaluated the potential of simvastatin loaded into poly(lactic-co-glycolic acid) (PLGA) microspheres to heal critical size defects in rat calvaria.PLGA scaffolds (50:50 ratio) were synthesized as ... |
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Inhibition of apoptosis signal-regulating kinase 1 enhances endochondral bone formation by increasing chondrocyte survival.
Cell Death Dis. 5 , e1522, (2014) Endochondral ossification is the result of chondrocyte differentiation, hypertrophy, death and replacement by bone. The careful timing and progression of this process is important for normal skeletal bone growth and development, as well as fracture repair. Ap... |
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DNA methylation profiles in placenta and its association with gestational diabetes mellitus.
Exp. Clin. Endocrinol. Diabetes 123 , 282-8, (2015) Emerging evidences indicate that placenta plays a critical role in gestational diabetes mellitus (GDM). DNA methylation could be associated with altered placental development and functions. This study is to uncover the genome-wide DNA methylation patterns in ... |
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Octreotide inhibits the bilirubin carriers organic anion transporting polypeptides 1B1 and 1B3 and the multidrug resistance-associated protein 2.
J. Pharmacol. Exp. Ther. 355 , 145-51, (2015) The somatostatin analog octreotide can lead to hyperbilirubinemia without evidence of liver injury. Here we investigate whether octreotide inhibits the main sinusoidal/canalicular bilirubin carriers and whether it is a transport substrate. Octreotide showed t... |
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Bone-forming capacity of adult human nasal chondrocytes.
J. Cell. Mol. Med. 19 , 1390-9, (2015) Nasal chondrocytes (NC) derive from the same multipotent embryological segment that gives rise to the majority of the maxillofacial bone and have been reported to differentiate into osteoblast-like cells in vitro. In this study, we assessed the capacity of ad... |
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MiR137 is an androgen regulated repressor of an extended network of transcriptional coregulators.
Oncotarget 6 , 35710-25, (2015) Androgens and the androgen receptor (AR) play crucial roles in male development and the pathogenesis and progression of prostate cancer (PCa). The AR functions as a ligand dependent transcription factor which recruits multiple enzymatically distinct epigeneti... |
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Mineralization defects in cementum and craniofacial bone from loss of bone sialoprotein.
Bone 78 , 150-64, (2015) Bone sialoprotein (BSP) is a multifunctional extracellular matrix protein found in mineralized tissues, including bone, cartilage, tooth root cementum (both acellular and cellular types), and dentin. In order to define the role BSP plays in the process of bio... |
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Blocking the expression of both bone sialoprotein (BSP) and osteopontin (OPN) impairs the anabolic action of PTH in mouse calvaria bone.
J. Cell Physiol. 230(3) , 568-77, (2014) Osteopontin (OPN) and bone sialoprotein (BSP) are coexpressed in osteoblasts and osteoclasts, and display overlapping properties. We used daily injection of parathyroid hormone 1-84 (iPTH) over the calvaria of BSP knockout (-/-) mice to investigate further th... |