Oxantel (pamoate)
Oxantel (pamoate) structure
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Common Name | Oxantel (pamoate) | ||
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| CAS Number | 68813-55-8 | Molecular Weight | 604.65 | |
| Density | 1.09 g/cm3 | Boiling Point | 383.1ºC at 760 mmHg | |
| Molecular Formula | C36H32N2O7 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 185.5ºC | |
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Oxantel pamoate-albendazole for Trichuris trichiura infection.
N. Engl. J. Med. 370(7) , 610-20, (2014) Infections with soil-transmitted helminths (Ascaris lumbricoides, hookworm, and Trichuris trichiura) are widespread and often occur concomitantly. These parasitic-worm infections are typically treated with albendazole or mebendazole, but both drugs show low e... |
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Preventive anthelmintic chemotherapy--expanding the armamentarium.
N. Engl. J. Med. 370(7) , 665-6, (2014)
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Mechanisms underlying gut dysfunction in a murine model of chronic parasitic infection.
Am. J. Physiol. Gastrointest. Liver Physiol. 299 , G1354-G1360, (2010) Irritable bowel syndrome (IBS) is common in countries where chronic parasitic infestations are endemic. However, the relationship between parasitic infection and IBS is not clear. The aim of this study was to examine whether chronic parasitic infection is acc... |
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Activity of oxantel pamoate monotherapy and combination chemotherapy against Trichuris muris and hookworms: revival of an old drug.
PLoS Negl. Trop. Dis. 7(3) , e2119, (2013) It is widely recognized that only a handful of drugs are available against soil-transmitted helminthiasis, all of which are characterized by a low efficacy against Trichuris trichiura, when administered as single doses. The re-evaluation of old, forgotten dru... |
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Response of pre-adult and adult stages of Trichuris muris to common anthelmintics in mice.
Int. J. Parasitol. 21(6) , 697-702, (1991) The common anthelmintics, oxantel, mebendazole, albendazole and pyrantel were assessed for their comparative activity against Trichuris muris in mice. Mice were infected with T. muris and the infection was maintained by a brief cortisone administration during... |
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Intestinal protozoan and helminth infections and control of soil-transmitted helminths in Malay school children.
Public Health 98(3) , 152-6, (1984)
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Treatment of Trichuris trichiura infection with a single dose of oxantel pamoate.
Scand. J. Infect. Dis. 14(4) , 297-9, (1982) 166 patients with trichuriasis have been treated at the Department of Tropical Diseases, Aurora Hospital, Helsinki, from January 1975 to October 1979. Final results could be confirmed in 141 patients. Thiabendazole was found discouraging, because of frequent ... |