68813-55-8
68813-55-8 structure
- Name: Oxantel (pamoate)
- Chemical Name: 4-[(3-carboxy-2-hydroxynaphthalen-1-yl)methyl]-3-hydroxynaphthalene-2-carboxylic acid,3-[(E)-2-(1-methyl-5,6-dihydro-4H-pyrimidin-2-yl)ethenyl]phenol
- CAS Number: 68813-55-8
- Molecular Formula: C36H32N2O7
- Molecular Weight: 604.65
- Catalog: analytical chemistry Standard Forensic and veterinary standards
- Create Date: 2018-07-24 17:11:56
- Modify Date: 2025-08-25 19:40:05
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Oxantel pamoate is a widely available dewormer, potently against Trichuris muris and Hookworms.
| Name | 4-[(3-carboxy-2-hydroxynaphthalen-1-yl)methyl]-3-hydroxynaphthalene-2-carboxylic acid,3-[(E)-2-(1-methyl-5,6-dihydro-4H-pyrimidin-2-yl)ethenyl]phenol |
|---|---|
| Synonyms |
Telopar (TN)
EINECS 272-332-6 UNII-UPY1D732T0 Telopar HMS2093L04 Oxantel embonate Oxantel pamoate (USAN) OXANTEL PAMOATE Oxantel (pamoate) |
| Description | Oxantel pamoate is a widely available dewormer, potently against Trichuris muris and Hookworms. |
|---|---|
| Related Catalog | |
| Target |
Antiparasitic[1] |
| In Vivo | The activity of the veterinary drug Oxantel pamoate is studied against Trichuris muris, Ancylostoma ceylanicum and Necator americanus. An ED50s of 4.7 mg/kg is calculated for Oxantel pamoate against T. muris in mice. Combinations of Oxantel pamoate with pyrantel pamoate behaved antagonistically (combination index (CI)=2.53). Oxantel pamoate combined with Levamisole, Albendazole or Ivermectin using ratios based on their ED50s reveals antagonistic effects (CI=1.27, 1.90 and 1.27, respectively). A highly synergistic effect (CI=0.15) is observed when Oxantel pamoate-mebendazole is administered to T. muris-infected mice. Oxantel pamoate (10 mg/kg) lacks activity against Ancylostoma ceylanicum and Necator americanus[1]. |
| References |
| Density | 1.09 g/cm3 |
|---|---|
| Boiling Point | 383.1ºC at 760 mmHg |
| Molecular Formula | C36H32N2O7 |
| Molecular Weight | 604.65 |
| Flash Point | 185.5ºC |
| PSA | 186.72000 |
| LogP | 7.41720 |
| Storage condition | -20℃ |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |