Benzylamine hydrochloride

Benzylamine hydrochloride Structure
Benzylamine hydrochloride structure
Common Name Benzylamine hydrochloride
CAS Number 3287-99-8 Molecular Weight 143.614
Density N/A Boiling Point 185ºC at 760 mmHg
Molecular Formula C7H10ClN Melting Point 262-263 °C(lit.)
MSDS Chinese USA Flash Point 60ºC
Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger

Investigation of the sunscreen octocrylene's interaction with amino acid analogs in the presence of UV radiation.

Photochem. Photobiol. 88(4) , 904-12, (2012)

Octocrylene is an organic UV filter, commonly used in sunscreens and cosmetics, which can give rise to both contact and photocontact allergy. Our aim was to investigate octocrylene's interaction with amino acid analogs in the presence of UV radiation to bette...

Benzylamine antihyperglycemic effect is abolished by AOC3 gene invalidation in mice but not rescued by semicarbazide-sensitive amine oxidase expression under the control of aP2 promoter.

J. Physiol. Biochem. 68(4) , 651-62, (2012)

Semicarbazide-sensitive amine oxidase (SSAO) is a transmembrane enzyme that metabolizes primary amines from endogenous or dietary origin. SSAO is highly expressed in adipose, smooth muscle and endothelial cells. In each of these cell types, SSAO is implicated...

Functional modulation of vascular adhesion protein-1 by a novel splice variant.

PLoS ONE 8(1) , e54151, (2013)

Vascular Adhesion Protein-1 (VAP-1) is an endothelial adhesion molecule belonging to the primary amine oxidases. Upon inflammation it takes part in the leukocyte extravasation cascade facilitating transmigration of leukocytes into the inflamed tissue. Screeni...

[Liver monoamine oxidase activity of the lamprey Lampetra fluviatilis. the substrate-inhibitory specificity].

Zh. Evol. Biokhim. Fiziol. 49(1) , 39-43, (2013)

Based on data of substrate-inhibitory analysis with use of specific inhibitors--deprenyl, chlorgi-lin--and specific substrates--serotonin, noradrenalin, benzylamine, beta-phenylethylamine, and N-methylhistamine--a suggestion is put forward about the possible ...

Selective monoamine oxidase B inhibition by an Aphanizomenon flos-aquae extract and by its constitutive active principles phycocyanin and mycosporine-like amino acids.

Phytomedicine 21(7) , 992-7, (2014)

Aphanizomenon flos-aquae (AFA) is a fresh water unicellular blue-green alga that has been traditionally used for over 25 years for its health-enhancing properties. Recent studies have shown the ability of a proprietary AFA extract (Klamin(®)) to improve mood,...

A seven-coordinated manganese(II) complex with V-shaped ligand bis(N-benzylbenzimidazol-2-ylmethyl)benzylamine: synthesis, structure, DNA-binding properties and antioxidant activities.

J. Photochem. Photobiol. B, Biol. 116 , 13-21, (2012)

A manganese(II) complex of the type, [MnL(pic)(2)]·H(2)O, was obtained by the reaction of the V-shaped ligand bis(N-benzylbenzimidazol-2-ylmethyl)benzylamine (L) with Mn(pic)(2) (pic=picrate). The ligand L and Mn(II) complex were confirmed on the basis of ele...

SSAO substrates exhibiting insulin-like effects in adipocytes as a promising treatment option for metabolic disorders.

Future Med. Chem. 2(12) , 1735-49, (2010)

Benzylamine exerts insulin-like effects in adipocytes (e.g., glucose uptake and antilipolysis) and improves glucose handling in rodents.In murine adipocytes, benzylamine mimics another insulin action: it enhances apelin expression in a manner that is blocked ...

Derivatization of (5R)-hydroxytriptolide from benzylamine to enhance mass spectrometric detection: application to a Phase I pharmacokinetic study in humans.

Anal. Chim. Acta 689(1) , 69-76, (2011)

(5R)-Hydroxytriptolide, a semisynthetic structural analog of triptolide, exhibits anti-inflammatory and immunosuppressive effect both in vitro and in vivo. The compound is currently undergoing Phase I clinical trials. This work describes the quantification of...

Reaction of vascular adhesion protein-1 (VAP-1) with primary amines: mechanistic insights from isotope effects and quantitative structure-activity relationships.

J. Biol. Chem. 286(34) , 29584-93, (2011)

Human vascular adhesion protein-1 (VAP-1) is an endothelial copper-dependent amine oxidase involved in the recruitment and extravasation of leukocytes at sites of inflammation. VAP-1 is an important therapeutic target for several pathological conditions. We e...

Inhibition of bovine plasma semicarbazide-sensitive amine oxidase by caffeine.

J. Biochem. Mol. Toxicol. 25(1) , 26-7, (2011)

Semicarbazide-sensitive amine oxidase (SSAO) is a copper-containing enzyme that catalyzes the oxidative deamination of endogenous and exogenous primary amines. SSAO exists in mammals both as a plasma-soluble and as a membrane-bound form, and its active site i...