Hypophosphorous acid

Hypophosphorous acid Structure
Hypophosphorous acid structure
Common Name Hypophosphorous acid
CAS Number 6303-21-5 Molecular Weight 65.996
Density 1.206 g/mL at 20 °C(lit.) Boiling Point 108 °C (759.8513 mmHg)
Molecular Formula H4O4P2 Melting Point -25 °C
MSDS Chinese USA Flash Point N/A
Symbol GHS05
GHS05
Signal Word Danger

Bidirectional regulation of synaptic plasticity in the basolateral amygdala induced by the D1-like family of dopamine receptors and group II metabotropic glutamate receptors.

J. Physiol. 592(Pt 19) , 4329-51, (2014)

Competing mechanisms of long-term potentiation (LTP) and long-term depression (LTD) in principal neurons of the basolateral amygdala (BLA) are thought to underlie the acquisition and consolidation of fear memories, and their subsequent extinction. However, no...

Presynaptic GABAB autoreceptor regulation of nicotinic acetylcholine receptor mediated [(3)H]-GABA release from mouse synaptosomes.

Biochem. Pharmacol. 91(1) , 87-96, (2014)

Activation of nicotinic acetylcholine receptors (nAChRs) can elicit neurotransmitter release from presynaptic nerve terminals. Mechanisms contributing to cell-and-terminal specific regulation of nAChR-mediated neurotransmitter exocytosis are not fully underst...

Exposure to repeated immobilization stress inhibits cocaine-induced increase in dopamine extracellular levels in the rat ventral tegmental area.

Pharmacol. Res. 101 , 116-23, (2015)

A higher vulnerability to drug abuse has been observed in human studies of individuals exposed to chronic or persistent stress, as well as in animal models of drug abuse. Here, we explored the effect of repeated immobilization stress on cocaine-induced increa...

High-Performance Flexible All-Solid-State Supercapacitor from Large Free-Standing Graphene-PEDOT/PSS Films.

Sci. Rep. 5 , 17045, (2015)

Although great attention has been paid to wearable electronic devices in recent years, flexible lightweight batteries or supercapacitors with high performance are still not readily available due to the limitations of the flexible electrode inventory. In this ...

Adenosine modulates light responses of rat retinal ganglion cell photoreceptors througha cAMP-mediated pathway.

J. Physiol. 592(Pt 19) , 4201-20, (2014)

Adenosine is an established neuromodulator in the mammalian retina, with A1 adenosine receptors being especially prevalent in the innermost ganglion cell layer. Activation of A1 receptors causes inhibition of adenylate cyclase, decreases in intracellular cycl...

Mechanisms underlying the renoprotective effect of GABA against ischaemia/reperfusion-induced renal injury in rats.

Clin. Exp. Pharmacol. Physiol. 42(3) , 278-86, (2015)

Excitation of the renal sympathetic nervous system is important for the development of ischaemic acute kidney injury (AKI) in rats. We reported that intravenous treatment with GABA has preventive effects against ischaemia/reperfusion (I/R)-induced renal dysfu...

Biosynthesis of phosphonic and phosphinic acid natural products.

Annu. Rev. Biochem. 78 , 65-94, (2009)

Natural products containing carbon-phosphorus bonds (phosphonic and phosphinic acids) have found widespread use in medicine and agriculture. Recent years have seen a renewed interest in the biochemistry and biology of these compounds with the cloning of the b...

Phosphinic acid compounds in biochemistry, biology and medicine.

Curr. Med. Chem. 7(6) , 629-47, (2000)

This review summarizes our knowledge of biochemical, biological and medical applications and properties of phosphinic acid compounds. Phosphinic acid compounds (phosphinates) are derivatives of phosphinic acid H2P(O)(OH). The major attention of this article i...

Phosphorylation of synapsin I by cyclin-dependent kinase-5 sets the ratio between the resting and recycling pools of synaptic vesicles at hippocampal synapses.

J. Neurosci. 34(21) , 7266-80, (2014)

Cyclin-dependent kinase-5 (Cdk5) was reported to downscale neurotransmission by sequestering synaptic vesicles (SVs) in the release-reluctant resting pool, but the molecular targets mediating this activity remain unknown. Synapsin I (SynI), a major SV phospho...

The Kinetics and Mechanism of the Oxidation of Hypophosphorous Acid by Cerium (IV) in Perchloric Acid Solution. Carroll RL and Thomas LB.

J. Am. Chem. Soc. 88(7) , 1376-1381, (1996)