Hydroxyzine dihydrochloride
Hydroxyzine dihydrochloride structure
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Common Name | Hydroxyzine dihydrochloride | ||
|---|---|---|---|---|
| CAS Number | 2192-20-3 | Molecular Weight | 447.826 | |
| Density | 1.182 g/cm3 | Boiling Point | 499.2ºC at 760 mmHg | |
| Molecular Formula | C21H29Cl3N2O2 | Melting Point | 190-192°C | |
| MSDS | Chinese USA | Flash Point | 255.7ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Microencapsulation of hydroxyzine HCl by thermal phase separation: in vitro release enhancement and in vivo pharmacodynamic evaluation.
Pharm. Dev. Technol. 18(1) , 196-209, (2013) The systemic effect of hydroxyzine hydrochloride following its oral administration or topical application is associated with non compliant anticholinergic effect. Subsequently, the present study aims to prepare microcapsules loaded with hydroxyzine hydrochlor... |
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Worsening of contact dermatitis by oral hydroxyzine: a case report.
Dermatol. Online J. 19(2) , 4, (2013) Hydroxyzine is commonly used to treat pruritic skin lesions. Although rare, hydroxyzine can sometimes be linked to worsening dermatitis in patients who have sensitivities to phenothiazines and/or ethylenediamines. Herein we describe a patient who developed pa... |
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Development and validation of an ultra-performance liquid chromatography method for simultaneous analysis of 20 antihistaminics in dietary supplements.
Biomed. Chromatogr. 29(3) , 465-74, (2015) The purpose of this study was to develop and validate an ultra-performance liquid chromatography method for simultaneous analysis of 20 antihistamines (illegal additives) in dietary supplements. The limits of detection and quantitation of the method ranged fr... |
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Acute generalized exanthematous pustulosis associated with 2 common medications: hydroxyzine and benzocaine.
J. Am. Acad. Dermatol. 71(4) , e147-9, (2014)
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A fatality due to an accidental methadone substitution in a dental cocktail.
J. Anal. Toxicol. 35(7) , 512-5, (2011) A 6-year-old male child was scheduled for a dental procedure requiring conscious sedation. Prior to the procedure, the child was administered a dental cocktail containing chloral hydrate, hydroxyzine, and methadone. After returning from the dentist, the child... |
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Sedation of children undergoing dental treatment.
Cochrane Database Syst. Rev. 3 , CD003877, (2012) Children's fear about dental treatment may lead to behaviour management problems for the dentist, which can be a barrier to the successful dental treatment of children. Sedation can be used to relieve anxiety and manage behaviour in children undergoing dental... |
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LSD screening in urine performed by CEDIA® LSD assay: positive interference with sertraline.
J. Anal. Toxicol. 36(4) , 289-90, (2012)
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Anaphylactic reaction to povidone secondary to drug ingestion in a young child
Allergol. Immunopathol. (Madr.) 40(4) , 259-61, (2012)
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Assessing the removal of pharmaceuticals and personal care products in a full-scale activated sludge plant.
Environ. Sci. Pollut. Res. Int. 19(5) , 1818-27, (2012) This study aimed to investigate the removal mechanisms of pharmaceutical active compounds (PhACs) and musks in a wastewater treatment plant (WWTP). Biological removal and adsorption in the activated sludge tank as well as the effect of UV radiation used for d... |
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Two-step liquid phase microextraction combined with capillary electrophoresis: a new approach to simultaneous determination of basic and zwitterionic compounds.
J. Sep. Sci. 35(15) , 1959-66, (2012) In this work, two-step hollow fiber-based liquid-phase microextraction procedure was evaluated for extraction of the zwitterionic cetirizine (CTZ) and basic hydroxyzine (HZ) in human plasma. In the first step of extraction, the pH of sample was adjusted at 5.... |