BW-723C86
BW-723C86 structure
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Common Name | BW-723C86 | ||
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| CAS Number | 160521-72-2 | Molecular Weight | 322.853 | |
| Density | N/A | Boiling Point | 488.4ºC at 760 mmHg | |
| Molecular Formula | C16H19ClN2OS | Melting Point | 203 - 205 °C | |
| MSDS | USA | Flash Point | 249.2ºC | |
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Pronociceptive and Antinociceptive Effects of Buprenorphine in the Spinal Cord Dorsal Horn Cover a Dose Range of Four Orders of Magnitude.
J. Neurosci. 35 , 9580-94, (2015) Due to its distinct pharmacological profile and lower incidence of adverse events compared with other opioids, buprenorphine is considered a safe option for pain and substitution therapy. However, despite its wide clinical use, little is known about the synap... |
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BW 723C86, a 5-HT2B receptor agonist, causes hyperphagia and reduced grooming in rats.
Neuropharmacology 36 , 233-239, (1997) The 5-HT2B receptor agonist, BW 723C86 (10 and 20 mg/kg s.c.), increased the time spent in feeding behaviour of freely-fed rats in observation cages over 15 min. BW 723C86 (20 and 50 mg/kg s.c. 30 min pre-test) also modestly increased food consumption of free... |
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Effects of the 5-HT2B receptor agonist, BW 723C86, on three rat models of anxiety.
Br. J. Pharmacol. 117 , 1443-1448, (1996) 1. BW 723C86 (3 and 10 mg kg-1, s.c. 30 min pretest), a 5-HT2B receptor agonist, increased total interaction, but not locomotion in a rat social interaction test, a profile consistent with anxiolysis. 2. The effect of BW 723C86 in the social interaction test ... |
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Serotonin Is Involved in Autoimmune Arthritis through Th17 Immunity and Bone Resorption.
Am. J. Pathol. 186 , 927-37, (2016) Rheumatoid arthritis is a chronic disease that results in a disabling and painful condition as it progresses to destruction of the articular cartilage and ankylosis of the joints. Although the cause of the disease is still unknown, evidence argues that autoim... |
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Expression and function of serotonin 2A and 2B receptors in the mammalian respiratory network.
PLoS ONE 6 , e21395, (2011) Neurons of the respiratory network in the lower brainstem express a variety of serotonin receptors (5-HTRs) that act primarily through adenylyl cyclase. However, there is one receptor family including 5-HT(2A), 5-HT(2B), and 5-HT(2C) receptors that are direct... |