(±)-7-Hydroxy-2-(di-n-propylamino)tetralin hydrobromide
(±)-7-Hydroxy-2-(di-n-propylamino)tetralin hydrobromide structure
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Common Name | (±)-7-Hydroxy-2-(di-n-propylamino)tetralin hydrobromide | ||
|---|---|---|---|---|
| CAS Number | 159795-63-8 | Molecular Weight | 328.28800 | |
| Density | N/A | Boiling Point | 383.8ºC at 760 mmHg | |
| Molecular Formula | C16H26BrNO | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 178.5ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Chemical genetics reveals a complex functional ground state of neural stem cells.
Nat. Chem. Biol. 3(5) , 268-273, (2007) The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain cancer. However, the complete repertoire of signaling pathways ... |
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Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Nat. Chem. Biol. 5 , 765-71, (2009) Studies of gene function and molecular mechanisms in Plasmodium falciparum are hampered by difficulties in characterizing and measuring phenotypic differences between individual parasites. We screened seven parasite lines for differences in responses to 1,279... |
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Lentiviral vector-mediated dopamine d3 receptor modulation in the rat brain impairs alcohol intake and ethanol-induced conditioned place preference.
Alcohol. Clin. Exp. Res. 38(9) , 2369-76, (2014) It has been reported that dopamine D3 receptor (D3R) knockout mice display similar ethanol (EtOH) consumption compared to wild types. In addition, studies with D3R pharmacological targeting were inconclusive.In the current study, we used both gain- and loss-o... |
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Dopaminergic modulation of rat pup ultrasonic vocalizations.
Eur. J. Pharmacol. 382 , 53, (1999) The dopamine D(1) receptor agonist, R(+)-6-chloro-7, 8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide (SKF 81297), the dopamine D(2)/D(3) receptor agonist, trans-(-)-4aR-4,4a,5,6,7,8,8a,9-octahydro-5-propyl-1H-pyrazolo[3, 4-g]quinoline hy... |
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Anxiolytic-like effects of preferential dopamine D3 receptor agonists in an animal model.
Pol. J. Pharmacol. 55(3) , 449-54, (2003) The aim of the present study was to examine a potential anxiolytic-like action of (+)-7-hydroxy-2-(di-n-propylamino)tetralin hydrobromide (7-OH-DPAT), a preferential dopamine D(3) receptor agonist, and (N-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]-2-naphthy... |
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Effects of dopamine D(1-like) and D(2-like) agonists in rats that self-administer cocaine.
J. Pharmacol. Exp. Ther. 291 , 353, (1999) The reinforcing effects of D(1-like) and D(2-like) agonists, and their capacity to modify cocaine self-administration, were compared in rats with extensive cocaine self-administration experience. Cocaine (0.01-1.0 mg i.v.) dose-dependently maintained respondi... |
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Effect of antidepressant drugs administered repeatedly on the dopamine D3 receptors in the rat brain.
Eur. J. Pharmacol. 351 , 31, (1998) Previous studies have indicated that antidepressant drugs displaying different pharmacological profiles, administered repeatedly, increase the locomotor hyperactivity induced by various dopaminomimetics, among others by quinpirole. As this drug, according to ... |
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Dopaminergic regulation of mate competition aggression and aromatase-Fos colocalization in vasotocin neurons.
Neuropharmacology 58 , 117-25, (2010) Recent experiments demonstrate that aggressive competition for potential mates involves different neural mechanisms than does territorial, resident-intruder aggression. However, despite the obvious importance of mate competition aggression, we know little abo... |