Acridine
Acridine structure
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Common Name | Acridine | ||
|---|---|---|---|---|
| CAS Number | 260-94-6 | Molecular Weight | 179.217 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 346.7±11.0 °C at 760 mmHg | |
| Molecular Formula | C13H9N | Melting Point | 106-109 °C | |
| MSDS | Chinese USA | Flash Point | 153.8±11.9 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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In vitro toxicological assessment of iron oxide, aluminium oxide and copper nanoparticles in prokaryotic and eukaryotic cell types.
Drug Chem. Toxicol. 38 , 152-61, (2015) Metallic nanoparticles (NPs) have a variety of applications in different industries including pharmaceutical industry where these NPs are used mainly for image analysis and drug delivery. The increasing interest in nanotechnology is largely associated with un... |
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By promoting cell differentiation, miR-100 sensitizes basal-like breast cancer stem cells to hormonal therapy.
Oncotarget 6(4) , 2315-30, (2015) Basal-like breast cancer is an aggressive tumor subtype with a poor response to conventional therapies. Tumor formation and relapse are sustained by a cell subset of Breast Cancer Stem Cells (BrCSCs). Here we show that miR-100 inhibits maintenance and expansi... |
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The ionization mechanisms in direct and dopant-assisted atmospheric pressure photoionization and atmospheric pressure laser ionization.
J. Am. Soc. Mass Spectrom. 25(11) , 1870-81, (2014) A novel, gas-tight API interface for gas chromatography-mass spectrometry was used to study the ionization mechanism in direct and dopant-assisted atmospheric pressure photoionization (APPI) and atmospheric pressure laser ionization (APLI). Eight analytes (et... |
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Convenient QSAR model for predicting the complexation of structurally diverse compounds with β-cyclodextrins
Bioorg. Med. Chem. 17 , 896-904, (2009) This paper reports a QSAR study for predicting the complexation of a large and heterogeneous variety of substances (233 organic compounds) with beta-cyclodextrins (beta-CDs). Several different theoretical molecular descriptors, calculated solely from the mole... |
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Mouse model for sublethal Leptospira interrogans infection.
Infect. Immun. 83 , 4693-700, (2015) Although Leptospira can infect a wide range of mammalian species, most studies have been conducted in golden Syrian hamsters, a species particularly sensitive to acute disease. Chronic disease has been well characterized in the rat, one of the natural reservo... |
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Non-animal photosafety screening for complex cosmetic ingredients with photochemical and photobiochemical assessment tools.
Regul Toxicol Pharmacol 72 , 578-85, (2015) Previously, a non-animal screening approach was proposed for evaluating photosafety of cosmetic ingredients by means of in vitro photochemical and photobiochemical assays; however, complex cosmetic ingredients, such as plant extracts and polymers, could not b... |
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In silico and in vitro filters for the fast estimation of skin permeation and distribution of new chemical entities.
J. Med. Chem. 50 , 742-8, (2007) The development of in silico and in vitro tools to estimate or predict the passive human skin permeation and distribution of new chemical entities, useful in dermal drug delivery, in absorption studies of toxic compounds, and in the cosmetics industry, is pre... |
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Thymoquinone inhibits murine leukemia WEHI-3 cells in vivo and in vitro.
PLoS ONE 9(12) , e115340, (2014) Thymoquinone is an active ingredient isolated from Nigella sativa (Black Seed). This study aimed to evaluate the in vitro and in vivo anti-leukemic effects of thymoquinone on WEHI-3 cells.The cytotoxic effect of thymoquinone was assessed using an MTT assay, w... |
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Antitumor activity of acriflavine in lung adenocarcinoma cell line A549.
Anticancer Res. 34(11) , 6467-72, (2014) Aim/Materials and Methods: In order to develop better drugs against non-small cell lung cancer (NSCLC), we screened a variety of compounds and treated the human lung adenocarcinoma cell line A549 with different drug concentrations. We then examined the cell v... |
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Online Investigation of Aqueous-Phase Electrochemical Reactions by Desorption Electrospray Ionization Mass Spectrometry.
J. Am. Soc. Mass Spectrom. 26 , 1676-85, (2015) Electrochemistry (EC) combined with mass spectrometry (MS) is a powerful tool for elucidation of electrochemical reaction mechanisms. However, direct online analysis of electrochemical reaction in aqueous phase was rarely explored. This paper presents the onl... |