2,6-Dimethyl-γ-pyrone

2,6-Dimethyl-γ-pyrone Structure
2,6-Dimethyl-γ-pyrone structure
Common Name 2,6-Dimethyl-γ-pyrone
CAS Number 1004-36-0 Molecular Weight 124.14
Density 1.1±0.1 g/cm3 Boiling Point 249.0±0.0 °C at 760 mmHg
Molecular Formula C7H8O2 Melting Point 133-137 °C(lit.)
MSDS Chinese USA Flash Point 103.4±12.3 °C
Symbol GHS07
GHS07
Signal Word Warning

In silico identification and biochemical characterization of novel inhibitors of NQO1.

Bioorg. Med. Chem. Lett. 16 , 6246-54, (2006)

From in silico docking and COMPARE analysis, novel inhibitors of human NAD(P)H quinone oxidoreductase (NQO1) have been identified from the NCI compound database, the most potent of which has an observed IC(50) of 0.7muM. The inhibitors exhibit a diverse range...