Ethyl carbamimidothioate hydrobromide (1:1)
Ethyl carbamimidothioate hydrobromide (1:1) structure
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Common Name | Ethyl carbamimidothioate hydrobromide (1:1) | ||
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| CAS Number | 1071-37-0 | Molecular Weight | 185.09 | |
| Density | 1.19 g/cm3 | Boiling Point | 159.6ºC at 760 mmHg | |
| Molecular Formula | C3H9BrN2S | Melting Point | 79-81°C | |
| MSDS | Chinese USA | Flash Point | 50.3ºC | |
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Differential activity of NO synthase inhibitors as chemopreventive agents in a primary rat tracheal epithelial cell transformation system.
Neoplasia 4(4) , 332-6, (2002) A model to study the effectiveness of potential chemopreventive agents that inhibit neoplastic process by different mechanisms has been used to test the efficacy of seven nitric oxide synthase (NOS) inhibitors. Five selective inducible NOS (iNOS) inhibitors: ... |
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Inotropic response to endothelin-1, isoprenaline and calcium in cardiomyocytes isolated from endotoxin treated rats: effects of ethyl-isothiourea and dexamethasone.
Br. J. Pharmacol. 130(6) , 1275-82, (2000) 1. The contractile effects of endothelin-1, isoprenaline and extracellular calcium were assessed on ventricular cardiomyocytes isolated from lipopolysaccharide-treated rats. The involvement of nitric oxide was investigated using dexamethasone (in vivo) and et... |
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Inducible nitric oxide synthase inhibition attenuates renal hemodynamics during pregnancy.
Hypertension 39(2 Pt 2) , 586-90, (2002) Acute, nonselective nitric oxide synthase inhibition in the pregnant rat decreases glomerular filtration rate and renal plasma flow, suggesting a role for nitric oxide in mediating renal vasodilation during pregnancy. As mid-gestation in the rat is associated... |
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Possible role of nitric oxide in anxiety following transient cerebral ischemia in mice.
J. Pharmacol. Sci. 91(1) , 47-52, (2003) The possible role of nitric oxide (NO) in anxiety following transient cerebral ischemia by a 10-min bilateral carotid occlusion was examined in mice. Two days after the ischemia, mice showed a significant decrease in time spent on the open arms in the elevate... |
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Nitroarginine and tetrahydrobiopterin binding to the haem domain of neuronal nitric oxide synthase using a scintillation proximity assay.
Biochem. J. 332 ( Pt 1) , 195-201, (1998) Nitric oxide synthases (NOS) have a bidomain structure comprised of an N-terminal oxygenase domain and a C-terminal reductase domain. The oxygenase domain binds haem, (6R)-5,6,7,8-tetrahydro-l-biopterin (tetrahydrobiopterin) and arginine, is the site where ni... |
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Influence of different classes of NO synthase inhibitors in the pig gastric fundus.
Naunyn Schmiedebergs Arch. Pharmacol. 356(4) , 488-94, (1997) The inhibitory potency of different classes of nitric oxide synthase (NOS) inhibitors (amino acid-based substances, guanidines, isothioureas, imidazoles and indazoles) versus peripheral neuronal NOS in the pig gastric fundus was investigated by studying their... |
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Brain neuronal/inducible nitric oxide synthases and cyclooxygenase-1 are involved in the bombesin-induced activation of central adrenomedullary outflow in rats
Eur. J. Pharmacol. 590(1-3) , 177-84, (2008) Brain nitric oxide (NO) is mainly generated by neuronal NO synthase (NOS) and inducible NOS. In various cells, NO has been shown to regulate cyclooxygenase (COX), which is divided into two isoforms, COX-1 and COX-2. We previously reported that bombesin inject... |
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Nitric oxide synthase inhibitor (MTR-105) during open-heart surgery. A pilot double-blind placebo-controlled study of hemodynamic effects and safety.
Cardiology 111(3) , 181-7, (2008) Hypotension is common immediately following cardiopulmonary bypass. Experimentally, MTR-105 (S-ethylisothiuronium diethylphosphate), a fast-acting synthetic nitric oxide synthase inhibitor, rapidly increases blood pressure. The purpose of the current study wa... |
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Evidence for the presence of an unusual nitric oxide- and citrulline-producing enzyme in rat kidney.
Biochem. Biophys. Res. Commun. 232(3) , 672-7, (1997) We have found an enzymatic activity obtained from rat kidney capable of producing citrulline and NOx. (nitrate and nitrite) which was resistant to inhibition by conventional arginine analogues. This enzyme activity does not require any calcium or calmodulin a... |
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Measurement of upregulation of inducible nitric oxide synthase in the experimental autoimmune encephalomyelitis model using a positron emitting radiopharmaceutical.
Nitric Oxide 1(3) , 263-7, (1997) Excess nitric oxide has been implicated in the pathogenosis of experimental autoimmune encephalomyelitis (EAE) which is an animal model for multiple sclerosis. Positron emission tomography (PET) is an imaging technique that has shown utility for studying enzy... |