(S)-(+)-2-AMino-3-cyclohexyl-1-propanol hydrochloride

(S)-(+)-2-AMino-3-cyclohexyl-1-propanol hydrochloride Structure
(S)-(+)-2-AMino-3-cyclohexyl-1-propanol hydrochloride structure
Common Name (S)-(+)-2-AMino-3-cyclohexyl-1-propanol hydrochloride
CAS Number 117160-99-3 Molecular Weight 193.71400
Density 0.97g/cm3 Boiling Point 289.5ºC at 760mmHg
Molecular Formula C9H20ClNO Melting Point 230ºC (dec.)(lit.)
MSDS Chinese USA Flash Point 128.9ºC
Symbol GHS07
GHS07
Signal Word Warning

Renin inhibitors. Dipeptide analogues of angiotensinogen utilizing a dihydroxyethylene transition-state mimic at the scissile bond to impart greater inhibitory potency.

J. Med. Chem. 31 , 2264, (1988)

The synthesis of diol-containing renin inhibitors has revealed that a simple vicinal diol functionality corresponding to the scissile Leu-Val bond in human angiotensinogen is capable of imparting inhibitory activity at a comparable or higher level than either...