2,6-Dimethoxy-1,4-benzoquinone
2,6-Dimethoxy-1,4-benzoquinone structure
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Common Name | 2,6-Dimethoxy-1,4-benzoquinone | ||
|---|---|---|---|---|
| CAS Number | 530-55-2 | Molecular Weight | 168.147 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 311.1±42.0 °C at 760 mmHg | |
| Molecular Formula | C8H8O4 | Melting Point | 253-257 °C (dec.)(lit.) | |
| MSDS | Chinese USA | Flash Point | 139.2±27.9 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Oxidative depolymerization of lignin in ionic liquids.
ChemSusChem 3(6) , 719-23, (2010) Beech lignin was oxidatively cleaved in ionic liquids to give phenols, unsaturated propylaromatics, and aromatic aldehydes. A multiparallel batch reactor system was used to screen different ionic liquids and metal catalysts. Mn(NO(3))(2) in 1-ethyl-3-methylim... |
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Quinonoid constituents as contact sensitisers in Australian blackwood (Acacia melanoxylon RBR).
Br. J. Ind. Med. 38(2) , 105-9, (1981) Australian blackwood (Acacia melanoxylon RBR) is a valuable commercial timber that since 1925 has been incriminated as being injurious to health. In addition to toxic effects numerous cases of allergic contact dermatitis and bronchial asthma have been observe... |
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Orchid allergy.
Arch. Dermatol. 120(9) , 1206-8, (1984) A female office worker acquired contact allergy by handling Cymbidium cultivars for several years. The sensitizing properties of this ornamental orchid were demonstrated by experimental sensitization of guinea pigs. Chemical analysis of the ether extracts dis... |
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1,4-Benzoquinone reductase from basidiomycete Phanerochaete chrysosporium: spectral and kinetic analysis.
Arch. Biochem. Biophys. 331(1) , 31-40, (1996) The reaction mechanism of a 1,4-benzoquinone reductase from the wood-rotting basidiomycete Phanerochaete chrysosporium was investigated. The native, oxidized, FMN-containing enzyme was reduced quantitatively by NADH and the resulting reduced enzyme was reoxid... |
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Synergism of dimethoxybenzosemiquinone free radicals and CD4+ T-lymphocytes to suppress Ehrlich ascites tumor.
Proc. Soc. Exp. Biol. Med. 217(1) , 89-96, (1998) Numerous natural and synthetic quinone compounds possess significant antitumor properties. Various mechanisms have been proposed to account for these properties, including scission and degradation of tumor cell DNA, intracellular "redox cycling" to cogenerate... |
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Cytotoxic, DNA-damaging and mutagenic properties of 2,6-dimethoxy-1,4-benzoquinone, formed by dimethophrine-nitrite interaction.
J. Pharmacol. Exp. Ther. 244(3) , 1011-5, (1988) In conditions similar to those occurring in the stomach, the sympathomimetic drug dimethophrine was found to react with nitrite yielding 2,6-dimethoxy-1,4-benzoquinone (DMBQ). The in vitro and in vivo studies carried out to evaluate the capability of DMBQ to ... |
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Formation of 2,6-dimethoxy-1,4-benzoquinone, a highly genotoxic compound, from the reaction of sodium nitrite with the sympathomimetic drug dimethophrine in acidic aqueous solution.
Farmaco. Sci. 43(6) , 523-38, (1988) Because of the genotoxic effects shown by Dimethophrine (DMP) nitrosation mixtures, the interaction between DMP hydrochloride and sodium nitrite in acidic aqueous solution at 37 degrees was investigated in a wide range of reagent concentrations and molar rati... |
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Non-mutagenicity of some wood-related compounds in the bacterial/microsome plate incorporation and microsuspension assays.
Int. Arch. Occup. Environ. Health 54(1) , 83-90, (1984) Seven commercially available wood-related compounds have been tested for mutagenicity by the use of the Ames and fluctuation test-systems. All compounds were found to be non-mutagenic. Among these compounds, 2,6-dimethoxy-p-benzoquinone showed a very weak and... |
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Inhibition of mast cell histamine release by 2,6-dimethoxy-p-benzoquinone isolated from Berchemia racemosa.
Chem. Pharm. Bull. 34(3) , 1333-6, (1986)
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Characterizing the efficacy of fermented wheat germ extract against ovarian cancer and defining the genomic basis of its activity.
Int. J. Gynecol. Cancer 22(6) , 960-7, (2012) Most women with advanced-stage epithelial ovarian cancer (OVCA) ultimately develop chemoresistant recurrent disease. Therefore, a great need to develop new, more active, and less toxic agents and/or to optimize the efficacy of existing agents exists.In this s... |