Detomidine hydrochloride
Detomidine hydrochloride structure
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Common Name | Detomidine hydrochloride | ||
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| CAS Number | 90038-01-0 | Molecular Weight | 222.714 | |
| Density | N/A | Boiling Point | 386.5ºC at 760mmHg | |
| Molecular Formula | C12H15ClN2 | Melting Point | 160ºC | |
| MSDS | N/A | Flash Point | 200.6ºC | |
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Atipamezole antagonism of an ACTH stimulation test in ponies sedated with detomidine.
J. Vet. Pharmacol. Ther. 34(5) , 508-11, (2011)
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Influence of detomidine and xylazine on spleen dimensions and on splenic response to epinephrine infusion in healthy adult horses.
Vet. Anaesth. Analg. 40(4) , 375-81, (2013) To compare the changes in splenic length and thickness and in packed cell volume (PCV) following detomidine or xylazine administration and subsequent epinephrine infusion.Spleen relaxation occurs following xylazine or detomidine administration and interferes ... |
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Comparison of the mechanical hypoalgesic effects of five α2-adrenoceptor agonists in donkeys.
Vet. Rec. 173(12) , 294, (2013) Pharmacological pain management is necessary under many clinical situations, but in donkeys little information on analgesic drugs is available. This controlled, randomised, crossover, Latin-square, operator-blinded study aimed to assess and compare the hypoal... |
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Accelerometric comparison of the locomotor pattern of horses sedated with xylazine hydrochloride, detomidine hydrochloride, or romifidine hydrochloride.
Am. J. Vet. Res. 74(6) , 828-34, (2013) To evaluate the duration of effects on movement patterns of horses after sedation with equipotent doses of xylazine hydrochloride, detomidine hydrochloride, or romifidine hydrochloride and determine whether accelerometry can be used to quantify differences am... |
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Comparison of butorphanol-detomidine versus butorphanol-azaperone for the standing sedation of captive greater one-horned rhinoceroses (Rhinoceros unicornis).
J. Zoo Wildl. Med. 45(1) , 60-8, (2014) Three adult and two subadult greater one-horned rhinoceroses (Rhinoceros unicornis) were sedated a total of nine times using two different intramuscular sedative combinations in order to compare the effectiveness of these combinations in inducing consistent s... |
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A controlled study evaluating a novel surgical treatment for kissing spines in standing sedated horses.
Vet. Surg. 41(7) , 890-7, (2012) To compare the results of a novel minimally invasive surgical technique with intralesional corticosteroid medication, as treatment for overriding dorsal spinous processes (ORDSP) in horses.Retrospective controlled clinical case series.Horses (n = 68) with ORD... |
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Evaluation of a butorphanol, detomidine, and midazolam combination for immobilization of captive Nile lechwe antelopes (Kobus magaceros).
J. Wildl. Dis. 48(3) , 739-46, (2012) Field immobilization of captive antelope may be required for medical examination, blood sample collection, and animal identification. The aim of this study was to evaluate the effects of a combination of butorphanol, detomidine, and midazolam (BDM) and its pa... |
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Electroretinogram responses of the normal thoroughbred horse sedated with detomidine hydrochloride.
Vet. Ophthalmol. 15 Suppl 2 , 77-83, (2012) The main objective was to record electroretinogram (ERG) parameters of normal thoroughbred mares using the HMsERG, a mini-Ganzfeld electroretinographic unit, and a contact lens electrode. The second objective was to determine whether IV detomidine hydrochlori... |
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Dehydration of detomidine hydrochloride monohydrate.
Eur. J. Pharm. Sci. 44(3) , 273-80, (2011) The thermodynamic stability of detomidine hydrochloride monohydrate has been evaluated on the basis of phase transition kinetics in solid state. A method free of empirical models was used for the treatment of kinetic data, and compared to several known solid ... |
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Reversible chemical restraint of free-range cattle with a concentrated combination of tiletamine-zolazepam, ketamine, and detomidine.
Can. J. Vet. Res. 77(4) , 288-92, (2013) The aim of this study was to determine the efficacy of a concentrated combination of tiletamine-zolazepam [TZ, 0.53 mg/kg body weight (BW)], ketamine (Ket, 0.53 mg/kg BW), and detomidine (Det, 0.04 mg/kg BW) in the immobilization of free-range cattle for clin... |