Semicarbazide
Semicarbazide structure
|
Common Name | Semicarbazide | ||
|---|---|---|---|---|
| CAS Number | 57-56-7 | Molecular Weight | 75.070 | |
| Density | 1.7±0.1 g/cm3 | Boiling Point | 186.3±23.0 °C at 760 mmHg | |
| Molecular Formula | CH5N3O | Melting Point | 175-185ºC /decomposes/ | |
| MSDS | Chinese USA | Flash Point | 66.5±22.6 °C | |
|
Rapid detection of economic adulterants in fresh milk by liquid chromatography-tandem mass spectrometry.
J. Chromatogr. A. 1288 , 10-20, (2013) A method to aid in the detection of the economically driven adulteration of fresh milk with a range of small, nitrogen containing compounds, including melamine, ammeline, ammelide, cyanuric acid, allantoin, thiourea, urea, biuret, triuret, semicarbazide, amin... |
|
|
Sphingosine 1-phosphate mediates hyperalgesia via a neutrophil-dependent mechanism.
PLoS ONE 8(1) , e55255, (2013) Novel classes of pain-relieving molecules are needed to fill the void between non-steroidal anti-inflammatory agents and narcotics. We have recently shown that intraplantar administration of sphingosine 1-phosphate (S1P) in rats causes peripheral sensitizatio... |
|
|
Functional modulation of vascular adhesion protein-1 by a novel splice variant.
PLoS ONE 8(1) , e54151, (2013) Vascular Adhesion Protein-1 (VAP-1) is an endothelial adhesion molecule belonging to the primary amine oxidases. Upon inflammation it takes part in the leukocyte extravasation cascade facilitating transmigration of leukocytes into the inflamed tissue. Screeni... |
|
|
Protective effect of the multitarget compound DPH-4 on human SSAO/VAP-1-expressing hCMEC/D3 cells under oxygen-glucose deprivation conditions: an in vitro experimental model of cerebral ischaemia.
Br. J. Pharmacol. 172 , 5390-402, (2016) Stroke and Alzheimer's disease (AD) are related pathologies in which the cerebrovascular system is involved. Plasma levels of semicarbazide-sensitive amine oxidase/vascular adhesion protein 1 (SSAO/VAP-1, also known as Primary Amine Oxidase -PrAO) are increas... |
|
|
Inhibition of semicarbazide-sensitive amine oxidase attenuates myocardial ischemia-reperfusion injury in an in vivo rat model.
Leuk. Res. 88 , 302-6, (2011) This study tested the hypothesis that the inhibition of semicarbazide-sensitive amine oxidase (SSAO) after ischemia could attenuate myocardial ischemia-reperfusion (I/R) injury.Anesthetized male Sprague-Dawley rats underwent myocardial I/R injury. Saline, sem... |
|
|
SSAO substrates exhibiting insulin-like effects in adipocytes as a promising treatment option for metabolic disorders.
Future Med. Chem. 2(12) , 1735-49, (2010) Benzylamine exerts insulin-like effects in adipocytes (e.g., glucose uptake and antilipolysis) and improves glucose handling in rodents.In murine adipocytes, benzylamine mimics another insulin action: it enhances apelin expression in a manner that is blocked ... |
|
|
Assessment of the determination of azodicarbonamide and its decomposition product semicarbazide: investigation of variation in flour and flour products.
J. Agric. Food Chem. 59(17) , 9313-8, (2011) Azodicarbonamide, as a bleaching agent and improving agent, is a permitted food additive in certain countries and can be determined by high-performance liquid chromatography. However, it partially degrades with the heat of processing to form trace amounts of ... |
|
|
Semicarbazide is non-specific as a marker metabolite to reveal nitrofurazone abuse as it can form under Hofmann conditions.
Food Addit. Contam. Part A. Chem. Anal. Control. Expo. Risk Assess. 26(1) , 47-56, (2009) Detecting illegal nitrofurazone treatment of food-producing animals has been undermined by the reliance on semicarbazide as a marker metabolite for analysis because, during processing, semicarbazide forms in a variety of foods not exposed to nitrofurazone by ... |
|
|
Extracellular serotonin level in the basolateral nucleus of the amygdala and dorsal periaqueductal gray under unconditioned and conditioned fear states: Anin vivomicrodialysis study
Brain Res. 1294 , 106-15, (2009) Serotonin (5-HT) plays a key role in the neural circuitry mediating unconditioned and conditioned fear responses related to panic and generalized anxiety disorders. The basolateral nucleus of the amygdala (BLA) and the dorsal periaqueductal gray (dPAG) appear... |
|
|
Comparative studies by IR, Raman, and surface-enhanced Raman spectroscopy of azodicarbonamide, biurea and semicarbazide hydrochloride.
Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 114 , 80-4, (2013) Azodicarbonamide is widely applied in the food industry as a new flour gluten fortifier in China, Canada, the United States, and some other countries, whose metabolites of biurea and semicarbazide hydrochloride are reaction products during baking. In this stu... |