Semicarbazide

Modify Date: 2024-01-04 09:16:28

Semicarbazide Structure
Semicarbazide structure
Common Name Semicarbazide
CAS Number 57-56-7 Molecular Weight 75.070
Density 1.7±0.1 g/cm3 Boiling Point 186.3±23.0 °C at 760 mmHg
Molecular Formula CH5N3O Melting Point 175-185ºC /decomposes/
MSDS Chinese USA Flash Point 66.5±22.6 °C

 Names

Name semicarbazide
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.7±0.1 g/cm3
Boiling Point 186.3±23.0 °C at 760 mmHg
Melting Point 175-185ºC /decomposes/
Molecular Formula CH5N3O
Molecular Weight 75.070
Flash Point 66.5±22.6 °C
Exact Mass 75.043259
PSA 81.14000
LogP -1.61
Vapour Pressure 0.2±0.8 mmHg at 25°C
Index of Refraction 1.602

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VT2975000
CHEMICAL NAME :
Semicarbazide
CAS REGISTRY NUMBER :
57-56-7
BEILSTEIN REFERENCE NO. :
0506319
LAST UPDATED :
199701
DATA ITEMS CITED :
11
MOLECULAR FORMULA :
C-H5-N3-O
MOLECULAR WEIGHT :
75.09
WISWESSER LINE NOTATION :
ZVMZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Human - man
DOSE/DURATION :
40 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
140 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
140 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
176 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
123 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
105 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
126 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
25 gm/kg/30W-C
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors

MUTATION DATA

TYPE OF TEST :
DNA repair
TEST SYSTEM :
Bacteria - Escherichia coli
DOSE/DURATION :
125 ug/well
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 133,161,1984

 Safety Information

Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes Xn
Risk Phrases 22
Safety Phrases S22
RIDADR NONH for all modes of transport
WGK Germany 3

 Articles45

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 Synonyms

aminourea
Urea,amino
Aminomocovina
Carbazamide
Semikarbazid
MFCD00042824
Carbazinamide
EINECS 200-339-6
amino-ure
Hydrazinecarboxamide
Carbamylhydrazine
Semicarbazide
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