U 19451A
U 19451A structure
|
Common Name | U 19451A | ||
|---|---|---|---|---|
| CAS Number | 538-28-3 | Molecular Weight | 202.704 | |
| Density | N/A | Boiling Point | 283.2ºC at 760mmHg | |
| Molecular Formula | C8H11ClN2S | Melting Point | 172-177 °C | |
| MSDS | Chinese USA | Flash Point | 125.1ºC | |
| Symbol |
GHS06 |
Signal Word | Danger | |
|
S-benzylisothiourea derivatives as small-molecule inhibitors of indoleamine-2,3-dioxygenase.
Bioorg. Med. Chem. Lett. 20 , 5126-9, (2010) S-benzylisothiourea 3a was discovered by its ability to inhibit indoleamine-2,3-dioxygenase (IDO) in our screening program. Subsequent optimization of the initial hit 3a lead to the identification of sub-muM inhibitors 3r and 10h, both of which suppressed kyn... |
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