Meticillin

Meticillin Structure
Meticillin structure
Common Name Meticillin
CAS Number 61-32-5 Molecular Weight 380.41600
Density N/A Boiling Point N/A
Molecular Formula C17H20N2O6S Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

Antimicrobial properties of membrane-active dodecapeptides derived from MSI-78.

Biochim. Biophys. Acta 1848(5) , 1139-46, (2015)

Antimicrobial peptides (AMPs) are a class of broad-spectrum antibiotics known by their ability to disrupt bacterial membranes and their low tendency to induce bacterial resistance, arising as excellent candidates to fight bacterial infections. In this study w...

Bacteriophage as effective decolonising agent for elimination of MRSA from anterior nares of BALB/c mice.

BMC Microbiol. 14 , 212, (2014)

Nasal carriers not only pose serious threat to themselves but also to the community by playing an active role in the dissemination of serious and life threatening S. aureus especially MRSA strains. The present study focuses on the use of broad spectrum lytic ...

Preparation and in vitro-in vivo evaluation of ofloxacin loaded ophthalmic nano structured lipid carriers modified with chitosan oligosaccharide lactate for the treatment of bacterial keratitis.

Eur. J. Pharm. Sci. 63 , 204-15, (2014)

The objective of this study was to explore the potential of the nanostructured lipid carriers (NLCs) modified with chitosan oligosaccharide lactate (COL) for topical ocular application. Ofloxacin (OFX) loaded NLCs were prepared by microemulsion or high shear ...

Nonstable Staphylococcus aureus Small-Colony Variants Are Induced by Low pH and Sensitized to Antimicrobial Therapy by Phagolysosomal Alkalinization.

J. Infect. Dis. 213 , 305-13, (2015)

Staphylococcus aureus-infected patients treated with antibiotics that are effective in vitro often experience relapse of infection because the bacteria hide in privileged locations. These locations include abscesses and host cells, which contain low-pH compar...

Methicillin-resistant Staphylococcus aureus (MRSA) detected at four U.S. wastewater treatment plants.

Environ. Health Perspect. 120(11) , 1551-8, (2012)

The incidence of community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) infections is increasing in the United States, and it is possible that municipal wastewater could be a reservoir of this microorganism. To date, no U.S. studies have eva...

Superbug hideout: finding MRSA in U.S.wastewater treatment plants.

Environ. Health Perspect. 120(11) , A437, (2012)

Potential of sequential treatment with minocycline and S. aureus specific phage lysin in eradication of MRSA biofilms: an in vitro study.

Appl. Microbiol. Biotechnol. 99(7) , 3201-10, (2015)

Lysins are novel class of anti-infectives which are derived from bacteriophage. In the present study, the potential of previously characterised phage borne endolysin MR-10 in eradicating methicillin-resistant Staphylococcus aureus (MRSA) biofilm was evaluated...

Synthesis and antimicrobial evaluation of 2-(p-substituted phenyl)-5-[(4-substituted piperazin-l-yl)acetamido]-benzoxazoles.

Z. Naturforsch., C, J. Biosci. 69(9-10) , 368-74, (2015)

A series of 2-(p-substituted phenyl)-5-(2-{4-[(p-chloro-fluorophenyl)/phenyl] piperazin-1-yl}acetamido)-benzoxazoles were synthesized and tested for their antimicrobial activities. The structures of the new derivatives were elucidated by spectral techniques. ...

In vitro antibacterial effects of Cinnamomum extracts on common bacteria found in wound infections with emphasis on methicillin-resistant Staphylococcus aureus.

J. Ethnopharmacol. 153(3) , 587-95, (2014)

Cinnamomum species have been widely used in many traditional systems of medicine around the world. In the Malaysian traditional system of medicine, the leaves, stem bark and stem wood of Cinnamomum iners, Cinnamomum porrectum, Cinnamomum altissimum and Cinnam...

Targeting methicillin-resistant Staphylococcus aureus with short salt-resistant synthetic peptides.

Antimicrob. Agents Chemother. 58(7) , 4113-22, (2014)

The seriousness of microbial resistance combined with the lack of new antimicrobials has increased interest in the development of antimicrobial peptides (AMPs) as novel therapeutics. In this study, we evaluated the antimicrobial activities of two short synthe...