terameprocol

terameprocol Structure
terameprocol structure
Common Name terameprocol
CAS Number 24150-24-1 Molecular Weight 358.471
Density 1.0±0.1 g/cm3 Boiling Point 458.5±40.0 °C at 760 mmHg
Molecular Formula C22H30O4 Melting Point N/A
MSDS Chinese USA Flash Point 108.8±34.2 °C
Symbol GHS09
GHS09
Signal Word Warning

Terameprocol, a novel site-specific transcription inhibitor with anticancer activity.

Drugs 3rd ed., 11 , 204-214, (2008)

Terameprocol, a novel, semisynthetic derivative of a naturally occurring plant lignan, is under development by Erimos Pharmaceuticals LLC for the potential treatment of cancer. The antitumor activity of terameprocol is based on the selective inhibition of spe...

Tetra-O-Methyl Nordihydroguaiaretic Acid Broadly Suppresses Cancer Metabolism and Synergistically Induces Strong Anticancer Activity in Combination with Etoposide, Rapamycin and UCN-01.

PLoS ONE 11 , e0148685, (2016)

The ability of Tetra-O-methyl nordihydroguaiaretic acid (M4N) to induce rapid cell death in combination with Etoposide, Rapamycin, or UCN-01 was examined in LNCaP cells, both in cell culture and animal experiments. Mice treated with M4N drug combinations with...

Synthesis of apolipoprotein B lipoparticles to deliver hydrophobic/amphiphilic materials.

ACS Appl. Mater. Interfaces 5 , 7509-16, (2013)

To develop a drug delivery system (DDS), it is critical to address challenging tasks such as the delivery of hydrophobic and amphiphilic compounds, cell uptake, and the metabolic fate of the drug delivery carrier. Low-density lipoprotein (LDL) has been acknow...