9-Aminophenanthrene
9-Aminophenanthrene structure
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Common Name | 9-Aminophenanthrene | ||
|---|---|---|---|---|
| CAS Number | 947-73-9 | Molecular Weight | 193.24400 | |
| Density | 1.208g/cm3 | Boiling Point | 408.2ºC at 760mmHg | |
| Molecular Formula | C14H11N | Melting Point | 137-139ºC(lit.) | |
| MSDS | Chinese USA | Flash Point | 224.4ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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"Allosterism" in the elementary steps of the cytochrome P450 reaction cycle.
Drug Metab. Rev. 36(2) , 219-30, (2004) Cytochrome P450-dependent drug metabolism in vitro frequently deviates from simple Michaelis-Menten kinetic models, and demonstrates both positive and negative homotropic and heterotropic effects. These complex "allsoteric" kinetics confound our ability to pr... |
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Fluorometric high-performance liquid chromatography of 9-aminophenanthrene-derivatized free fatty acids.
J. Chromatogr. A. 305(2) , 261-70, (1984) The application of 9-aminophenanthrene (9-AP), a fluorescence-labeling reagent for free fatty acids (FFA), was examined. 9-AP dissolved in benzene was added to a benzene solution of FFA chlorides derived from FFA and oxalyl chloride. The mixture was allowed t... |
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HPLC on Chiralcel OJ-R for enantiomer separation and analysis of ketoprofen, from horse plasma, as the 9-aminophenanthrene derivative.
J. Pharm. Pharmacol. 50(3) , 291-6, (1998) Racemic ketoprofen is a non-steroidal anti-inflammatory drug used to treat musculoskeletal and colic conditions in horses. The enantioselective chiral inversion of ketoprofen administered to horses has been studied by use of cellulose tris(4-methylbenzoate), ... |
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7-Benzyloxyquinoline oxidation by P450eryF A245T: finding of a new fluorescent substrate probe.
Chem. Res. Toxicol. 15(6) , 806-14, (2002) The main objective of the present study was to find a fluorescent substrate probe for cytochrome P450eryF (P450eryF). P450eryF is a bacterial P450 that catalyzes the hydroxylation of 6-deoxyerythronolide B at the 6S position, a necessary step in the biosynthe... |
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NMR studies of ligand binding to P450(eryF) provides insight into the mechanism of cooperativity.
Biochemistry 45(6) , 1673-84, (2006) Cytochrome P450's (P450's) catalyze the oxidative metabolism of most drugs and toxins. Although extensive studies have proven that some P450's demonstrate both homotropic and heterotropic cooperativity toward a number of substrates, the mechanistic and molecu... |