MST312
MST312 structure
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Common Name | MST312 | ||
|---|---|---|---|---|
| CAS Number | 368449-04-1 | Molecular Weight | 380.35100 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H16N2O6 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS09 |
Signal Word | Warning | |
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MST-312 Alters Telomere Dynamics, Gene Expression Profiles and Growth in Human Breast Cancer Cells.
J. Nutrigenet. Nutrigenomics 7 , 283-98, (2015) Targeting telomerase is a potential cancer management strategy given that it allows unlimited cellular replication in the majority of cancers. Dysfunctional telomeres are recognized as double-strand breaks. However, the status of DNA repair response pathways ... |
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Fluorescence-based duplex-quadruplex competition test to screen for telomerase RNA quadruplex ligands.
Nucleic Acids Res. 39 , e21, (2011) RNA and DNA guanine-rich sequences can adopt unusual structures called Guanine quadruplexes (G4). A quadruplex-prone RNA sequence is present at the 5'-end of the 451-nt-long RNA component of telomerase, hTERC. As this quadruplex may interfere with P1 helix fo... |
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