Psora-4
Psora-4 structure
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Common Name | Psora-4 | ||
|---|---|---|---|---|
| CAS Number | 724709-68-6 | Molecular Weight | 334.36500 | |
| Density | 1.246g/cm3 | Boiling Point | 537.7ºC at 760 mmHg | |
| Molecular Formula | C21H18O4 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 279ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Psora-4, a Kv1.3 Blocker, Enhances Differentiation and Maturation in Neural Progenitor Cells.
CNS Neurosci. Ther. 21 , 558-67, (2015) The self-repair ability of neural progenitor cells (NPCs) has been found to be activated and protected in several therapies helpful in multiple sclerosis (MS), an inflammatory demyelinating disease of the CNS. As a potential therapeutic target in MS, the role... |
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K+ channels as targets for specific immunomodulation.
Trends Pharmacol. Sci. 25 , 280-289, (2004) The voltage-gated Kv1.3 channel and the Ca(2+)-activated IKCa1 K(+) channel are expressed in T cells in a distinct pattern that depends on the state of lymphocyte activation and differentiation. The channel phenotype changes during the progression from the re... |
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Kv1.3-blocking 5-phenylalkoxypsoralens: a new class of immunomodulators.
Mol. Pharmacol. 65 , 1364-1374, (2004) The lymphocyte potassium channel Kv1.3 is widely regarded as a promising new target for immunosuppression. To identify a potent small-molecule Kv1.3 blocker, we synthesized a series of 5-phenylalkoxypsoralens and tested them by whole-cell patch clamp. The mos... |