2-Chloro-6-cyanopyridine

2-Chloro-6-cyanopyridine Structure
2-Chloro-6-cyanopyridine structure
Common Name 2-Chloro-6-cyanopyridine
CAS Number 33252-29-8 Molecular Weight 138.554
Density 1.3±0.1 g/cm3 Boiling Point 245.3±20.0 °C at 760 mmHg
Molecular Formula C6H3ClN2 Melting Point 85-89 °C
MSDS Chinese USA Flash Point 102.1±21.8 °C
Symbol GHS05 GHS06
GHS05, GHS06
Signal Word Danger

A user-friendly, all-purpose Pd-NHC (NHC=N-heterocyclic carbene) precatalyst for the negishi reaction: a step towards a universal cross-coupling catalyst.

Chemistry 12 , 4749, (2006)

We have developed the first user-friendly Negishi protocol capable of routinely cross-coupling all combinations of alkyl and aryl centers. The use of an easily synthesized, air stable, highly active, well-defined precatalyst PEPPSI-IPr (1; PEPPSI=pyridine-enh...