BiCAPPA
BiCAPPA structure
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Common Name | BiCAPPA | ||
|---|---|---|---|---|
| CAS Number | 119662-55-4 | Molecular Weight | 683.66900 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C38H40Cl2N6O2 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Protein aggregation and neurodegenerative disease.
Nat. Med. 10 Suppl , S10-S17 , (2004) Neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD), amyotrophic lateral sclerosis (ALS) and prion diseases are increasingly being realized to have common cellular and molecular mechanisms including... |
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Potent inhibition of scrapie prion replication in cultured cells by bis-acridines.
Proc. Natl. Acad. Sci. U. S. A. 100 , 3416-3421, (2003) Prion diseases are characterized by an accumulation of PrP(Sc), a misfolded isoform of the normal cellular prion protein, PrP(C). We previously reported the bioactivity of acridine-based compounds against PrP(Sc) replication in scrapie-infected neuroblastoma ... |
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