Bradykinin acetate salt

Bradykinin acetate salt Structure
Bradykinin acetate salt structure
Common Name Bradykinin acetate salt
CAS Number 6846-03-3 Molecular Weight 1060.208
Density 1.5±0.1 g/cm3 Boiling Point N/A
Molecular Formula C50H73N15O11 Melting Point N/A
MSDS USA Flash Point N/A

Detection of nitric oxide production in cell cultures by luciferin-luciferase chemiluminescence.

Biochem. Biophys. Res. Commun. 465 , 232-8, (2015)

A chemiluminescent method is proposed for quantitation of NO generation in cell cultures. The method is based on activation of soluble guanylyl cyclase by NO. The product of the guanylyl cyclase reaction, pyrophosphate, is converted to ATP by ATP sulfurylase ...

Simultaneous fragmentation of multiple ions using IMS drift time dependent collision energies.

J. Am. Soc. Mass Spectrom. 19 , 411-9, (2008)

Ion mobility spectrometry coupled with mass spectrometry (IMS-MS) was utilized to evaluate an ion collision energy ramping technique that simultaneously fragments a variety of species. To evaluate this technique, the fragmentation patterns of a mixture of ion...

Homocysteine inhibition of endothelium-dependent nitric oxide-mediated dilation of porcine retinal arterioles via enhanced superoxide production.

Invest. Ophthalmol. Vis. Sci. 54(3) , 2288-95, (2013)

Elevated plasma concentration of homocysteine, a sulfur-containing amino acid, is an emerging risk factor for cardiovascular diseases. Recent epidemiologic studies have confirmed that elevated homocysteine levels are associated with ocular vascular diseases; ...

Hydrogen sulfide in the mouse ductus arteriosus: a naturally occurring relaxant with potential EDHF function.

Am. J. Physiol. Heart Circ. Physiol. 304(7) , H927-34, (2013)

We have previously reported that bradykinin relaxes the fetal ductus arteriosus via endothelium-derived hyperpolarizing factor (EDHF) when other naturally occurring relaxants (prostaglandin E2, nitric oxide, and carbon monoxide) are suppressed, but the identi...

High-resolution separation of peptides by sodium dodecyl sulfate-polyacrylamide gel "focusing".

Electrophoresis 29 , 1749-52, (2008)

As a follow-up of our previous report (Anal. Chem. 2007, 79, 821-827) on analytical SDS-PAGE focusing, a refinement of the method for separation of peptides in the small to medium M(r) range (0.5-10 kDa) is here reported, based on a shallow gradient of immobi...

Bradykinin controls pool size of sensory neurons expressing functional δ-opioid receptors.

J. Neurosci. 33(26) , 10762-71, (2013)

Analgesics targeting the δ-opioid receptor (DOR) may lead to fewer side effects than conventional opioid drugs, which mainly act on μ-opioid receptors (MOR), because of the less abundant expression of DOR in the CNS compared with MOR. Analgesic potential of D...

Nonhistaminergic idiopathic angioedema: clinical response to icatibant.

J. Investig. Allergol. Clin. Immunol. 22(7) , 520-1, (2012)

Antihypertensive and renoprotective effect of the kinin pathway activated by potassium in a model of salt sensitivity following overload proteinuria.

Am. J. Physiol. Renal Physiol. 304(12) , F1399-410, (2013)

The albumin overload model induces proteinuria and tubulointersitial damage, followed by hypertension when rats are exposed to a hypersodic diet. To understand the effect of kinin system stimulation on salt-sensitive hypertension and to explore its potential ...

HAE update: determining optimal patient specific therapy.

Allergy Asthma Proc. 34(1) , 7-12, (2013)

Hereditary angioedema (HAE) is a rare autosomal dominant disease caused by deficient or dysfunctional C1 inhibitor (C1 INH). HAE patients experience recurrent episodes of angioedema affecting the extremities, face, genitalia or submucosal edema in the abdomen...

Bradykinin B2 receptor contributes to the exaggerated muscle mechanoreflex in rats with femoral artery occlusion.

Am. J. Physiol. Heart Circ. Physiol. 304(8) , H1166-74, (2013)

Static muscle contraction activates the exercise pressor reflex, which in turn increases sympathetic nerve activity (SNA) and blood pressure (BP). Bradykinin (BK) is considered as a muscle metabolite responsible for modulation of the sympathetic and cardiovas...