Endosulfan
Endosulfan structure
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Common Name | Endosulfan | ||
|---|---|---|---|---|
| CAS Number | 115-29-7 | Molecular Weight | 406.925 | |
| Density | 2.0±0.1 g/cm3 | Boiling Point | 449.7±45.0 °C at 760 mmHg | |
| Molecular Formula | C9H6Cl6O3S | Melting Point | 106ºC | |
| MSDS | Chinese USA | Flash Point | 225.8±28.7 °C | |
| Symbol |
GHS06, GHS09 |
Signal Word | Danger | |
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Interactions of endosulfan and methoxychlor involving CYP3A4 and CYP2B6 in human HepaRG cells.
Drug Metab. Dispos. 42(8) , 1235-40, (2014) Humans are usually exposed to several pesticides simultaneously; consequently, combined actions between pesticides themselves or between pesticides and other chemicals need to be addressed in the risk assessment. Many pesticides are efficient activators of pr... |
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Inhibition of voltage-gated calcium channels as common mode of action for (mixtures of) distinct classes of insecticides.
Toxicol. Sci. 141(1) , 103-11, (2014) Humans are exposed to distinct structural classes of insecticides with different neurotoxic modes of action. Because calcium homeostasis is essential for proper neuronal function and development, we investigated the effects of insecticides from different clas... |
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Persistent organic pollutant levels in human visceral and subcutaneous adipose tissue in obese individuals--depot differences and dysmetabolism implications.
Environ. Res. 133 , 170-7, (2014) The role of persistent organic pollutants (POPs) with endocrine disrupting activity in the aetiology of obesity and other metabolic dysfunctions has been recently highlighted. Adipose tissue (AT) is a common site of POPs accumulation where they can induce adv... |
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Reductive transformation of endosulfan in aqueous phase using magnesium-palladium bimetallic systems: a comparative study.
J. Hazard. Mater. 246-247 , 245-56, (2013) The efficiencies of reductive transformation of endosulfan by bimetallic systems consisting of zerovalent magnesium (Mg(0)) as the electron donor and three forms of palladium as the catalyst (Pd(0)-alumina, Pd(0)-carbon and Pd-K(2)PdCl(6)) were compared in th... |
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Neonatal exposure to low doses of endosulfan induces implantation failure and disrupts uterine functional differentiation at the pre-implantation period in rats.
Mol. Cell. Endocrinol. 401 , 248-59, (2015) We investigated whether neonatal exposure to low doses of endosulfan affects fertility and uterine functional differentiation at pre-implantation in rats. Newborn female rats received the vehicle, 0.2 µg/kg/d of diethylstilbestrol (DES), 6 µg/kg/d of endosulf... |
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Development of a new cucumber reference material for pesticide residue analysis: feasibility study for material processing, homogeneity and stability assessment.
Anal. Bioanal. Chem 407(11) , 3083-91, (2015) The feasibility of the production of a reference material for pesticide residue analysis in a cucumber matrix was investigated. Cucumber was spiked at 0.075 mg/kg with each of the 15 selected pesticides (acetamiprid, azoxystrobin, carbendazim, chlorpyrifos, c... |
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Environmental contaminants activate human and polar bear (Ursus maritimus) pregnane X receptors (PXR, NR1I2) differently.
Toxicol. Appl. Pharmacol. 284(1) , 54-64, (2015) Many persistent organic pollutants (POPs) accumulate readily in polar bears because of their position as apex predators in Arctic food webs. The pregnane X receptor (PXR, formally NR1I2, here proposed to be named promiscuous xenobiotic receptor) is a xenobiot... |
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Potential involvement of chemicals in liver cancer progression: an alternative toxicological approach combining biomarkers and innovative technologies.
Toxicol. In Vitro 28(8) , 1507-20, (2014) Pesticides as well as many other environmental pollutants are considered as risk factors for the initiation and the progression of cancer. In order to evaluate the in vitro effects of chemicals present in the diet, we began by combining viability, real-time c... |
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Assessment of endosulfan induced genotoxicity and mutagenicity manifested by oxidative stress pathways in freshwater cyprinid fish crucian carp (Carassius carassius L.).
Chemosphere 120 , 273-83, (2014) Over the past few decades, endosulfan, one of the polychlorinated pesticides still in use, has received considerable attention of a number of international regulations and restriction action plans worldwide. This study aimed to evaluate the cytogenetic effect... |
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Cardiotoxicity and apoptotic activity in subacute endosulfan toxicity and the protective effect of vitamin C in rabbits: a pathological study.
J. Environ. Pathol. Toxicol. Oncol. 32(1) , 53-8, (2013) Cardiovascular disease is one of the most significant causes of mortality in humans and animals, and its etiology is usually unknown. The aim of this study was to investigate the cardiac pathology of endosulfan toxicity and the protective effect of vitamin C ... |