2-(3,4-Dihydroxyphenyl)ethanol
2-(3,4-Dihydroxyphenyl)ethanol structure
|
Common Name | 2-(3,4-Dihydroxyphenyl)ethanol | ||
|---|---|---|---|---|
| CAS Number | 10597-60-1 | Molecular Weight | 154.163 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 355.4±27.0 °C at 760 mmHg | |
| Molecular Formula | C8H10O3 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 182.6±18.3 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
|
Bioconversion of oleuropein to hydroxytyrosol by lactic acid bacteria.
World J. Microbiol. Biotechnol. 28(6) , 2435-40, (2012) The aim of this work is to study the conversion of oleuropein-a polyphenol present in olives and olive oil by-products-into hydroxytyrosol, a polyphenol with antioxidant and antibacterial properties. The hydrolysis reaction is performed by lactic acid bacteri... |
|
|
Factors influencing phenolic compounds in table olives (Olea europaea).
J. Agric. Food Chem. 60(29) , 7081-95, (2012) The Mediterranean diet appears to be associated with a reduced risk of several chronic diseases including cancer and cardiovascular and Alzheimer's diseases. Olive products (mainly olive oil and table olives) are important components of the Mediterranean diet... |
|
|
Identification of the factors responsible for the in vitro pro-oxidant and cytotoxic activities of the olive polyphenols oleuropein and hydroxytyrosol.
Cancer Lett. 330(1) , 113-21, (2013) The olive polyphenols oleuropein and hydroxytyrosol were reported recently to produce extracellular hydrogen peroxide (H2O2) under standard culture conditions. The precise factors responsible for this production and the conditions promoting or retarding it ar... |
|
|
Oleuropein, a secoiridoid derived from olive tree, inhibits the proliferation of human colorectal cancer cell through downregulation of HIF-1α.
Nutr. Cancer 65(1) , 147-56, (2013) Oleuropein (OL) is the most prominent phenolic compound in the fruit of olive tree. Although OL has shown powerful anticancer activity the underlying action mechanism remains largely unknown. The present study evaluated the effects of OL on hydroxityrosol (HT... |
|
|
Hydroxytyrosol ameliorates oxidative stress and mitochondrial dysfunction in doxorubicin-induced cardiotoxicity in rats with breast cancer.
Biochem. Pharmacol. 90(1) , 25-33, (2014) Oxidative stress is involved in several processes including cancer, aging and cardiovascular disease, and has been shown to potentiate the therapeutic effect of drugs such as doxorubicin. Doxorubicin causes significant cardiotoxicity characterized by marked i... |
|
|
Anti-apoptotic activity of hydroxytyrosol and hydroxytyrosyl laurate.
Food Chem. Toxicol. 55 , 248-56, (2013) Hydroxytyrosol (HyT) is a polyphenol primarily released in olive mill wastewater and in olive oil. In animal and cell model studies, HyT and its metabolites have strong antioxidant and antimicrobial activities, as well as beneficial effects on the cardiovascu... |
|
|
3,4 dihydroxyphenyl ethanol reduces secretion of angiogenin in human retinal pigment epithelial cells.
Br. J. Ophthalmol. 97(3) , 371-4, (2013) Age-related macular degeneration (AMD) is currently the leading cause of blindness in developed countries. Bevacizumab is a widely used anti-VEGF agent that is a commonly applied therapy for neovascular AMD; however, a consequence of bevacizumab therapy may b... |
|
|
Hydroxytyrosol, a natural molecule from olive oil, suppresses the growth of human hepatocellular carcinoma cells via inactivating AKT and nuclear factor-kappa B pathways
Cancer Lett. 347(1) , 79-87, (2014) The present study aimed to investigate the anti-cancer effects of hydroxytyrosol (HT) in human hepatocellular carcinoma (HCC) cells. Our results show that HT could inhibit proliferation, induce G2/M cell cycle arrest and apoptosis in human HCC cells. Mechanic... |
|
|
Toxicological evaluation of pure hydroxytyrosol.
Food Chem. Toxicol. 55 , 498-504, (2013) Of all the phenolic constituents of olives and extra virgin olive oil, hydroxytyrosol is currently being actively exploited as a potential supplement or preservative to be employed in the nutraceutical, cosmeceutical, and food industry. In terms of safety pro... |
|
|
Self-assembled polymeric nanoparticles for percutaneous co-delivery of hydrocortisone/hydroxytyrosol: an ex vivo and in vivo study using an NC/Nga mouse model.
Int. J. Pharm. 444(1-2) , 109-19, (2013) In this study, hydroxytyrosol (HT; a potent antioxidant) was co-administered with hydrocortisone (HC) to mitigate the systemic adverse effects of the latter and to provide additional anti-inflammatory and antioxidant benefits in the treatment of atopic dermat... |