alpha-Toluenesulfonyl chloride

alpha-Toluenesulfonyl chloride Structure
alpha-Toluenesulfonyl chloride structure
Common Name alpha-Toluenesulfonyl chloride
CAS Number 1939-99-7 Molecular Weight 190.647
Density 1.4±0.1 g/cm3 Boiling Point 288.2±19.0 °C at 760 mmHg
Molecular Formula C7H7ClO2S Melting Point 92-94 °C(lit.)
MSDS Chinese USA Flash Point 128.1±21.5 °C
Symbol GHS05
GHS05
Signal Word Danger

Placental immune response to apple allergen in allergic mothers.

J. Reprod. Immunol. 106 , 100-9, (2014)

The immunological milieu in the placenta may be crucial for priming the developing foetal immune system. Early imbalances may promote the establishment of immune-mediated diseases in later life, including allergies. The initial exposure to allergens seems to ...

Polymeric micelles with citraconic amide as pH-sensitive bond in backbone for anticancer drug delivery.

Int. J. Pharm. 471(1-2) , 28-36, (2014)

A novel pH-sensitive polymeric micelle was reported. Methoxy poly(ethylene glycol)-b-poly(ϵ-caprolactone) copolymer with citraconic amide as pH-sensitive bond was synthesized (mPEG-pH-PCL). The copolymers self-assembled into micelles to encapsulate anticancer...

Roundabout 4 regulates blood-tumor barrier permeability through the modulation of ZO-1, Occludin, and Claudin-5 expression.

J. Neuropathol. Exp. Neurol. 74(1) , 25-37, (2014)

The blood-tumor barrier (BTB) restricts the delivery of chemotherapeutic drug molecules to tumor tissues. We found that the endothelial cell (EC) receptor molecule Roundabout 4 (Robo4) is endogenously expressed in human brain microvascular ECs and that it is ...

The long noncoding RNA TUG1 regulates blood-tumor barrier permeability by targeting miR-144.

Oncotarget 6 , 19759-79, (2015)

Blood-tumor barrier (BTB) limits the delivery of chemotherapeutic agent to brain tumor tissues. Long non-coding RNAs (lncRNAs) have been shown to play critical regulatory roles in various biologic processes of tumors. However, the role of lncRNAs in BTB perme...

The reaction of 1,1-bs(diethylamino)ethene with phenylmethanesulfonyl chloride.

J. Org. Chem. 30(1) , 71-4, (1965)

THE REACTION OF PHENYLMETHANESULFONYL CHLORIDE WITH TERTIARY AMINES: FORMATION OF GEOMETRICAL ISOMERS ABOUT A CARBON-SULFUR DOUBLE BOND. King JF and Durst T.

Can. J. Chem. 44(7) , 819-828, (1966)

Addition of Aliphatic Sulfonyl Chlorides to Enamines. Formation of Acyclic Products. Looker JJ.

J. Org. Chem. 31(9) , 2973-76, (1966)