3-(5-Nitro-2-furyl)acrylic Acid
3-(5-Nitro-2-furyl)acrylic Acid structure
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Common Name | 3-(5-Nitro-2-furyl)acrylic Acid | ||
|---|---|---|---|---|
| CAS Number | 6281-23-8 | Molecular Weight | 183.11800 | |
| Density | N/A | Boiling Point | 348.8ºC at 760 mmHg | |
| Molecular Formula | C7H5NO5 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 164.8ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Inducible stable DNA replication in Escherichia coli uvr+ and uvr- cells, treated with genotoxic chemicals.
Mutat. Res. 281(1) , 63-6, (1992) Inducible stable DNA replication (iSDR) provoked by a damaging treatment with MMS, MNU, MNNG, NFAA, NFN, 4NQO, NAL or MMC, was followed in both repair-competent E. coli PQ35 and its uvrA derivative E. coli PQ37. In contrast to SOS-inducible mutagenesis, which... |
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DNA damage by 5-nitro-2-furylacrylic acid, a nitrofuran derivative.
Chem. Biol. Interact. 63(2) , 185-94, (1987) 5-Nitro-2-furylacrylic acid (5-NFA) caused dose dependent inhibition of growth of Escherichia coli K-12 strain AB 2480 (uvr-, rec-), the 37% (D37) and 10% (D10) survival doses being 1.0 microgram/ml.h and 1.75 micrograms/ml.h, respectively. Although much high... |
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Mutagenic effects of two nitrofuran food preservatives.
Neoplasma 29(6) , 675-84, (1982) Two structurally related food additives, 3-(5-nitro-2-furyl)acrylic acid (5-NFAA) and 2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide (AF-2) showed a marked mutagenic effect on Salmonella typhimurium strains TA100 and TA98 and Escherichia coli WP2 uvrA+ and WP2 uvr... |
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Antimutagenicity of milk fermented by Enterococcus faecium.
Folia Microbiol. (Praha) 44(5) , 513-8, (1999) The diethyl ether extracts isolated from unfermented milk and milk fermented by Enterococcus faecium exhibited dose-dependent inhibition of mutagenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine (MNNG), nitrovin (NIT), 5-nitro-2-furylacrylic acid (NFA) a... |
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Antimicrobial effects of esters and amides of 3-(5-nitro-2-furyl)acrylic acid.
Folia Microbiol. (Praha) 29(1) , 23-34, (1984) The effect of 18 newly synthesized esters and amides of 3-(5-nitro-2-furyl)acrylic acid on bacteria (Escherichia coli, Staphylococcus aureus), yeasts (Saccharomyces cerevisiae, Candida albicans), molds (Aspergillus niger, Penicillium cyclopium, Rhizopus oryza... |
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Influence of ascorbic acid on the mutagenicity of N-methyl-N-nitrosoguanidine and nitrofurans studied by SOS chromotest.
Neoplasma 33(6) , 691-8, (1986) Mutagenicity inhibition of MNNG*, NFAA* as well as of nitrovin by ascorbic acid was observed. The influence of ascorbic acid on these compounds was parallelly studied also by spectroscopy. Mutagenicity inhibition was characterized by SOS chromotest. Inhibitio... |
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Mutagenic effects of nitrofurylacrylic acid on V79 cells under hypoxic conditions.
Neoplasma 30(1) , 7-12, (1983) Induction of 6-thioguanine-resistant mutations was studied in Chinese hamster V79 cells treated with nitrofurylacrylic acid under aerobic and hypoxic conditions. The results obtained demonstrated that the mutagenic activity of this substance, less significant... |
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Testing of mutagens and cigarette side smoke using a modified Salmonella assay.
Folia Microbiol. (Praha) 38(5) , 411-4, (1993) The results of two mutagens are presented in order to demonstrate the sensitivity of a modified Salmonella microsuspension assay (Kado et al. 1983) compared to the standard plate-incorporation assay. The first procedure was 2.4-7.3 times more sensitive in det... |
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[Analysis of the mutagenic activity of nitrofurylacrylic acid].
Vopr. Pitan. (4) , 63-7, (1981) The mutagenic activity of the vine stabilizer, sodium salt of 3-(5-nitro-2-furyl)acryl acid (5-NFA), was studied. Use was made of a cytogenetic analysis of mouse bone marrow cells, the dominant lethality test on male mice, analysis of chromosome aberrations i... |
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[On the contamination of the citric acid fermentation. II. Sodium 5-nitrofurylacrylate as an antiseptic against representatives of the Enterobacteriaceae (author's transl)].
Zentralbl. Bakteriol. Naturwiss. 134(7) , 611-6, (1979) In context with the first communication which deals with the characterization of the so-called brown contamination called forth by Enterobacteriaceae in the citric acid fermentation of molasses, the present paper describes the screening of antiseptic substanc... |