6-Bromohexanoic acid

6-Bromohexanoic acid Structure
6-Bromohexanoic acid structure
Common Name 6-Bromohexanoic acid
CAS Number 4224-70-8 Molecular Weight 195.054
Density 1.4±0.1 g/cm3 Boiling Point 279.2±0.0 °C at 760 mmHg
Molecular Formula C6H11BrO2 Melting Point 32-34 °C(lit.)
MSDS Chinese USA Flash Point 67.8±0.0 °C
Symbol GHS05
GHS05
Signal Word Danger

A Combination of Targeted Sunitinib Liposomes and Targeted Vinorelbine Liposomes for Treating Invasive Breast Cancer.

J. Biomed. Nanotechnol. 11 , 1568-82, (2015)

Regular chemotherapy cannot eradicate invasive breast cancer cells and the residual cancer cells will form vasculogenic mimicry (VM) channels under hypoxic conditions to provide nutrients for cancer masses prior to angiogenesis. This phenomenon is a major rea...

Mitochondria apoptosis pathway synergistically activated by hierarchical targeted nanoparticles co-delivering siRNA and lonidamine.

Biomaterials 61 , 178-89, (2015)

The mitochondria-mediated apoptosis pathway is an effective option for cancer therapy due to the presence of cell-suicide weapons in mitochondria. However, anti-apoptotic proteins that are over-expressed in the mitochondria of many malignant tumors, such as B...

Shared Ligands Between Organic Anion Transporters (OAT1 and OAT6) and Odorant Receptors.

Drug Metab. Dispos. 43 , 1855-63, (2015)

The multispecific organic anion drug transporters OAT6 (SLC22A20) and OAT1 (SLC22A6) are expressed in nasal epithelial cells and both can bind odorants. Sequence analysis of OAT6 revealed an evolutionarily conserved 79-amino acid (AA) fragment present not onl...

Cellular interaction and in vitro antitumor activity of mitomycin C-dextran conjugate.

Cancer Res. 46(9) , 4463-8, (1986)

Cellular interaction and in vitro antitumor activity of a polymeric prodrug of mitomycin C (MMC), mitomycin C-dextran conjugate (MMC-D), were studied in relation to its physicochemical characteristics. MMC-D with cationic and anionic charges were examined. Th...

Synthesis and antiestrogenic activity of diaryl thioether derivatives.

J. Med. Chem. 37 , 1115, (1994)

The reaction of 1,2-diarylethanol and mercapto side chain catalyzed by ZnI2 was used as a key step in the short (three to five steps) and efficient synthesis of 17 diaryl thioether derivatives. Several of these compounds contain a methyl butyl amide chain and...

Synthesis and tissue distribution of fluorine-18 labeled trifluorohexadecanoic acids. Considerations in the development of metabolically blocked myocardial imaging agents.

Bioconjug. Chem. 1(4) , 231-44, (1990)

A versatile method for the synthesis of trifluoro fatty acids, potential metabolically blocked myocardial imaging agents, has been developed. Two trifluorohexadecanoic (palmitic) acids have been prepared [6,6,16-trifluorohexadecanoic acid (I) and 7,7,16-trifl...

Orthogonal natural atomic orbitals form an appropriate one-electron basis for expanding CASSCF wave functions into localized bonding schemes and their weights.

Chem. Lett. 36 , 28, (2007)

Localized bonding schemes and their weights have been obtained for the pi-electron system of nitrone by expanding complete active space self-consistent field wave functions into a set of Slater determinants composed of orthogonal natural atomic orbitals (NAOs...

Tetrahedron Lett. 48 , 787, (2007)