5-iodo-1,3-dimethyluracil

5-iodo-1,3-dimethyluracil Structure
5-iodo-1,3-dimethyluracil structure
Common Name 5-iodo-1,3-dimethyluracil
CAS Number 40738-83-8 Molecular Weight 266.03600
Density 2.04g/cm3 Boiling Point 261.3ºC at 760 mmHg
Molecular Formula C6H7IN2O2 Melting Point 225ºC
MSDS Chinese USA Flash Point 111.8ºC
Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Danger

Unlabelled iododeoxyuridine increases the rate of uptake of [125I]iododeoxyuridine in human xenografted glioblastomas.

Eur. J. Nucl. Med. Mol. Imaging 29(4) , 499-505, (2002)

5-Iodo-2'-deoxyuridine (IdUrd), a thymidine (TdR) analogue, can be radiolabelled with iodine-125, an Auger radiation emitter, to provoke double-strand breaks once incorporated into DNA of cancer cells. We have previously shown that co-incubation of [125I]IdUr...

Synthesis and biological evaluation of new benzo-thieno[3,2-d]pyrimidin-4-one sulphonamide thio-derivatives as potential selective cyclooxygenase-2 inhibitors.

Mol. Divers. 17(3) , 445-58, (2013)

The aim of this work was to evaluate the potential anti-inflammatory activity of eleven (5-15) new synthesized derivatives of benzo-thieno[3,2-d]pyrimidine on two cell models, namely human keratinocytes NCTC 2544 and mouse monocyte-macrophages J774. For the s...

Organic iodine (I, III, and V) chemistry: 10 years of development at the Medical University of Warsaw, Poland. Skulski L.

Molecules 5(12) , 1331-71, (2000)