L-Phenylalanin amide hydrochloride

L-Phenylalanin amide hydrochloride Structure
L-Phenylalanin amide hydrochloride structure
Common Name L-Phenylalanin amide hydrochloride
CAS Number 65864-22-4 Molecular Weight 200.665
Density N/A Boiling Point 356.9ºC at 760 mmHg
Molecular Formula C9H13ClN2O Melting Point 234ºC
MSDS Chinese USA Flash Point 169.7ºC

Modified amino acids and peptides as substrates for the intestinal peptide transporter PepT1.

Eur. J. Biochem. 267(12) , 3723-8, (2000)

The binding affinities of a number of amino-acid and peptide derivatives by the mammalian intestinal peptide transporter PepT1 were investigated, using the Xenopus laevis expression system. A series of blocked amino acids, namely N-acetyl-Phe (Ac-Phe), phe-am...

Enantioseparation of dansyl amino acids by ligand-exchange capillary electrophoresis with zinc(II)-L-phenylalaninamide complex.

J. Sep. Sci. 32 , 3209-3214, (2009)

A novel method of chiral ligand-exchange CE was developed with L-amino acylamides as a chiral ligand and zinc(II) as a central ion. It has been demonstrated that these chiral complexes, such as Zn(II)-L-alaninamide, Zn(II)-L-prolinamide, and Zn(II)-L-phenylal...

In vitro selection of DNA aptamers that bind L-tyrosinamide.

Bioorg. Med. Chem. 9(10) , 2543-8, (2001)

We have applied SELEX (Systematic Evolution of Ligands by EXponential enrichment), a combinatorial method that employs biopolymers for drug discovery, to identify single stranded DNA sequences able to bind L-Tyrosinamide, a simple mimic of Tyrosine, an amino ...

Stability decrease of RNA double helices by phenylalanine-, tyrosine- and tryptophane-amides. Analysis in terms of site binding and relation to melting proteins.

Nucleic Acids Res. 10(19) , 6163-76, (1982)

The amides of L-phenylalanine, L-tyrosine and L-tryptophane decrease the melting temperatures tm of poly(A)*poly(U) and poly(I)*poly(C) double helices at low concentrations (1 mM), whereas high concentrations finally lead to an increase of tm. This dependence...

Biological properties of prolactin-releasing peptide analogs with a modified aromatic ring of a C-terminal phenylalanine amide.

Peptides 32(9) , 1887-92, (2011)

Prolactin-releasing peptide (PrRP)-induced secretion of prolactin is not currently considered a primary function of PrRP, but the development of late-onset obesity in both PrRP and PrRP receptor knock-out mice indicates the unique anorexigenic properties of P...

Chemically L-phenylalaninamide-modified monolithic silica column prepared by a sol-gel process for enantioseparation of dansyl amino acids by ligand exchange-capillary electrochromatography.

Anal. Chem. 73 , 3348-3357, (2001)

A new type of chiral monolithic column was successfully developed for the enantioseparation of dansyl amino acids by ligand exchange-capillary electrochromatography (LE-CEC) in this work. The monolithic column matrix was prepared by a sol-gel process and then...

Accurate measurement of cholecystokinin in plasma.

Clin. Chem. 44(5) , 991-1001, (1998)

Shortage of reliable plasma assays has hampered studies of cholecystokinin (CCK). The assay problems are low plasma concentrations, extensive molecular heterogeneity, and close homology of CCK to gastrin, which circulates in higher concentrations. To develop ...

[Stimulating action of polyphosphates on peptide formation from glycine and phenylalanine amides under abiogenic conditions].

Zh. Evol. Biokhim. Fiziol. 24(4) , 465-70, (1988)

Synthesis of peptides during polymerization of GlyNH2 and PheNH2 has been demonstrated by means of gel-chromatography and thin-layer chromatography. The optima of pH and temperature have been estimated for the reaction. Grem's salt, tripolyphosphate and pyrop...

Structures of D-amino-acid amidase complexed with L-phenylalanine and with L-phenylalanine amide: insight into the D-stereospecificity of D-amino-acid amidase from Ochrobactrum anthropi SV3.

Acta Crystallogr. D Biol. Crystallogr. 64(Pt 3) , 331-4, (2008)

The crystal structures of D-amino-acid amidase (DAA) from Ochrobactrum anthropi SV3 in complex with L-phenylalanine and with L-phenylalanine amide were determined at 2.3 and 2.2 A resolution, respectively. Comparison of the L-phenylalanine amide complex with ...

Synthesis, self-assembling properties, and atom transfer radical polymerization of an alkylated L-phenylalanine-derived monomeric organogel from silica: a new approach to prepare packing materials for high-performance liquid chromatography.

Chemistry 14(4) , 1312-21, (2008)

The monomer N'-octadecyl-N(alpha)-(4-vinyl)-benzoyl-L-phenylalanineamide (4) based on L-phenylalanine has been simply but effectively synthesized, and its self-assembling properties have been investigated. FTIR and a variable-temperature (1)H NMR spectroscopi...